方法：对110例青少年假性近视患者随机分两组治疗，对照组行10g/L硫酸阿托品眼用凝胶滴眼，观察组行5g/L消旋山莨菪碱滴眼液治疗。对比两种方法治疗30d后的疗效、眼轴长度、眼压的变化及不良反应的发生率。

结果：两组的治愈率比较，差异无统计学意义(χ²=0.533，P=0.465)，但观察组有效率显著优于对照组，差异具有统计学意义(χ²=3.907，P=0.048)。两组治疗30d后眼轴长度较组内治疗前均不同程度的增加，观察组增加值显著低于对照组，差异有统计学意义(P<0.05)，但两组治疗30d后水平比较差异无统计学意义(P>0.05)； 两组眼压较组内治疗前均显著下降，差异有统计学意义(P<0.05)，但两组间治疗30d后比较，差异无统计学意义(P>0.05)。不良反应发生率比较，观察组显著低于对照组，差异有统计学意义(χ²=18.939，P<0.05)。

结论：山莨菪碱滴眼液治疗青少年假性近视疗效显著，其疗效及安全性均优于阿托品眼用凝胶。

METHODS:Totally 110 cases of juvenile pseudomyopia were randomly divided into two groups, the control group was given 10g/L atropine sulfate eye gel, and the observation group was treated with 5g/L raceanisodamine eye drops. The efficacy of two methods, the changes of axial length and intraocular pressure before and after treatment, and the incidence of adverse reactions were compared.

RESULTS: There was no significant difference in cure rate between the two groups(χ²=0.533, P=0.465), but the effective rate of observation group was significantly better than the control group(χ²=3.907, P=0.048). Compared with the same group before treatment, the length of the axial length of the two groups increased in different degrees,and the increase value of the observation group was significantly higher than that of the control group, the difference was statistically significant(P<0.05), however, there was no significant difference between the two groups after treatment(P>0.05). The intraocular pressure of the two groups was significantly lower than that of the same group before treatment, and the difference between the two groups after treatments was not statistically significant(P >0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group(χ²=18.939, P<0.05).

CONCLUSION: Anisodamine eye drops in the treatment of juvenile pseudomyopia has obvious curative effect, its efficacy and safety are better than atropine eye gel.