目的：比较年龄相关性白内障患者手术前后闪光视觉诱发电位(flash visual evoked potential， FVEP)和图形视觉诱发电位(pattern visual evoked potential， PVEP)的变化及探讨其在评估术后视力中的意义。

方法：选取 2015-06/2016-05期间在我院治疗的年龄相关性白内障患者68例79眼， 分析手术前后FVEP及PVEP检测结果差异情况。对术前FVEP、PVEP 、FVEP 联合 PVEP检测结果与术后最佳矫正视力(BCVA)进行比较。

结果：FVEP检查术前、术后P2波潜时和N2-P2振幅的检测结果差异无统计学意义(t=0.448、-0.492，P>0.05)，PVEP检查术前、术后P100波潜时和N75-P100振幅的检测结果差异有统计学意义(t=2.505、-5.462，P<0.05)。术前FVEP的P2潜时及PVEP的P100潜时与术后BCVA呈负相关关系(r=-0.694，-0.402，P<0.05)，术前FVEP的N2-P2振幅与术后BCVA呈正相关关系(r=0.607，P<0.01)，术前PVEP的N75-P100振幅与术后BCVA无显著相关性(r=0.237，P>0.05)。FVEP检测一致率达到 83.54%， PVEP检测一致率为66.67%，差异有统计学意义(χ²=5.11，P<0.05)。FVEP 联合 PVEP检测一致率达到 90.74%， PVEP检测一致率为66.67%，差异有统计学意义(χ²=9.34，P<0.01)。

结论：FVEP相比于PVEP对年龄相关性白内障患者术后视力评估的稳定性更好，对术眼术前矫正视力≥0.1的患者FVEP 联合 PVEP检查能有效、客观地评估患者术后患眼视力恢复情况。

AIM: To compare the pre-and postoperation results of flash visual evoked potential(FVEP)and pattern visual evoked potential(PVEP)and to discuss the significance of FVEP and PVEP examinations in assessing postoperative visual acuity in senile cataract patients.

METHODS: During the period of June 2015 to May 2016, 68 cases of senile cataract patients(79 eyes)were treated in our hospital. This research analyzed the changes of pre- and postoperative FVEP and PVEP results and compared the preoperative FVEP, PVEP, FVEP combined with PVEP results with the postoperative best corrected visual acuity(BCVA).

RESULTS: There was no statistically significant difference in the incubation time of P2 wave and the amplitude of N2-P2 wave of FVEP pre-and postoperative examination(t=0.448, -0.492; P>0.05), there was statistically significant difference in the incubation time of P100 wave and the amplitude of N75-P100 wave of PVEP pre-and postoperative examination(t=2.505, -5.462; P<0.05).The incubation time of P2 and P100 wave before operation were significantly negatively correlated with the postoperative BCVA(r=-0.694, -0.402; P<0.05). The amplitude of N2-P2 wave before operation was significantly positively correlated with the postoperative BCVA(r=0.607,P<0.01). There was no significant correlation between the amplitude of N75-P100 wave before operation and the postoperative BCVA(r=0.237,P>0.05).Consistent rate of FVEP examination was 83.54%, that of PVEP was 66.67%, the difference was statistically significant(χ²=5.11,P<0.05).Consistent rate of FVEP combined with PVEP examination was 90.74%, that of PVEP was 66.67%, the difference was statistically significant(χ²=9.34,P<0.01).

CONCLUSION: By comparision, FVEP is better and more accurate than PVEP in predicting the postoperative visual acuity. Preoperative FVEP together with PVEP examinations can effectively and objectively assess postoperative visual function recovery of senile cataract patients whose corrected visual acuity of the proposed surgical eyes before operation is ≥0.1.