年龄相关性白内障防治药物的相关研究进展

Research progress of drugs that can control and prevent age-related cataract

摘要:

人眼晶状体是一个由上皮细胞以及其分化而来的纤维细胞共同组成的无血管透明器官。随着年龄的增长，晶状体混浊并可在一定程度上影响视力甚至致盲称为年龄相关性白内障(age-related cataract，ARC)，其公认的治疗手段为手术治疗，但一部分初发白内障也可通过药物控制其发生发展。本文就ARC相关防治药物及其重要成分进行介绍，并概括总结了近年来药物在白内障防治过程中的临床应用及研究进展。

Abstract:

The lens is a transparent tissue without vessel, which is mainly composed of a layer of epithelium cells and differentiating fiber cells. With aging, lens opacity can deteriorate vision significantly and even result in blindness, which is termed as age-related cataract(ARC). A fully developed treatment method of ARC is surgery, while a few cataracts in the initial stage can be suppressed via drugs efficiently.This paper introduced relevant drugs and important ingredients that can suppress and prevent ARC, and then summarizes clinical applications and existing researches with respect to drug treatments in the process of cataract suppression and treatment.