方法：选取西安市第一医院就诊的泪小管炎患者57例57眼，取泪小管分泌物行细菌培养及药敏试验； 对泪小管内排出的硫磺颗粒碾开涂片以寻找放线菌。

结果：泪小管炎患者57例57眼中，有56眼挤压泪小管见硫磺颗粒经泪点排出，取硫磺颗粒碾开涂片均见放线菌。57眼患眼取泪小管分泌物进行细菌培养，55眼为阳性，共培养出菌株63株，主要为表皮葡萄球菌、草绿色链球菌和肺炎球菌，其他菌种少见。药物敏感性试验结果显示：利福平、头孢西丁、氯霉素、美洛西林等药物敏感性较高。

结论：放线菌为泪小管炎的主要致病菌，且大部分存在于其他细菌的合并感染。利福平、头孢西丁、氯霉素、美洛西林等药物治疗泪小管炎敏感性高。

METHODS: Lacrimal sac secretion from 57 cases(57 eyes)with canalicular inflammation. used to do bacterial cultures and drug sensitivity tests. Grind open the sulfur particles from canaliculus for bacterial smear.

RESULTS: After squeeze canalicular, there are 56 sulfur granules from 57 patients. All of the Sulfur particles smears were found in actinomycetes. A total of 55 from 57 cases of lacrimal secretions for bacterial culture were positive, and 63 strains were cultured. The main pathogen are Staphylococcus epidermidis, Streptococcus viridans and pneumococcus. Drug susceptibility test results showed that: rifampicin, cefoxitin, chloramphenicol, and mezlocillin are sensitivity.

CONCLUSION: Actinomycetes were the main pathogens to canalicular inflammation, and most of the presence of co-infection with other bacteria. Rifampin, cefoxitin, chloramphenicol, and mezlocillin are sensitivity canalicular inflammation.