方法：选取原发性开角型青光眼患者14例24眼，均行Ex-press青光眼引流器植入术。收集术前裸眼视力、眼压、角膜内皮细胞计数、视野平均缺损(MD)、视野模式标准差(PSD)、视网膜神经纤维层厚度，术后1wk，1、3mo的裸眼视力、眼压，术后3mo的角膜内皮细胞计数、MD、PSD、视网膜神经纤维层厚度，观察随访期间的并发症及相关处理，统计手术成功率。

结果：术前，术后1wk，1、3mo裸眼视力分别进行两两比较，得出差异均无统计学意义(P>0.05)，术后视力无明显下降。术后1wk，1、3mo眼压与术前降低，差异有统计学意义(P<0.05)，且术后3mo内眼压保持平稳。术后3mo视网膜神经纤维层厚度和术前比较差异有统计学意义(P=0.018)。术后3mo MD绝对值和 PSD 较术前相比，差异均无统计学意义(P>0.05)。术后3mo的角膜内皮细胞较术前减少， 差异有统计学意义(Z=-2.585，P=0.01)。手术成功率：完全成功19眼(79%)，条件成功2眼(8%)，失败3眼(13%)。

结论：Ex-press青光眼引流器植入术术后短时间内可能会引起视网膜神经纤维层厚度变薄，稳定的降眼压效果能有效减缓视野进展，手术未影响视力，降眼压效果好，是治疗原发性开角型青光眼安全、有效的手术方法。

METHODS: A total of 14 patients(24 eyes)with POAG were underwent Ex-press glaucoma shunt implantation. Visual acuity, intraocular pressure(IOP), mean defect(MD), pattern standard deviation(PSD), retinal nerve fiber layer thickness(RNFLT), and corneal endothelial cell number were collected preoperatively. Visual acuity and IOP were collected in 1wk, 1 and 3mo postoperatively respectively. Also, MD, PSD, RNFLT, and corneal endothelial cell number were collected preoperatively and 3mo postoperatively respectively. Complication, the additional treatment, success rate were analyzed.

RESULTS: There was no significant difference(P>0.05)in visual acuity preoperative and postoperative 1wk, 1, 3mo. Visual acuity did not significantly reduce after operation. Compared with preoperative, there was significant decreased(P<0.05)in IOP after 1wk, 1, 3mo postoperative, respectively. IOP keep stead in postoperative 3mo. The reduction of RNFLT had significant difference(P<0.05)between preoperative and postoperative 3mo. Compared with preoperation, MD and PSD had no significant difference(P>0.05)after postoperative 3mo. Corneal endothelial cell number decrease had significant difference(Z=-2.585, P=0.01)between preoperative and postoperative 3mo. Success rate: complete success: 79.2%(19 eyes); partial success: 8.3%(2 eyes); failure: 12.5%(3 eyes).

CONCLUSION: Ex-press glaucoma shunt implantation could efficiently decrease the IOP in POAG patients. Although it results in reduction of RNFLT in short time. The visual acuity and visual field keep stable after operation. It is a safe and effective device for treating primary open-angle glaucoma.