方法：选取近视手术患者118例234眼，采用Keratron Scout角膜地形图仪分别于室内照明及暗室情况下进行检查，记录明暗瞳孔直径大小、明暗瞳孔时Kappa角的大小。

结果：左右眼明暗瞳孔直径大小的差异有统计学意义(P<0.01)。明瞳时，左右眼Kappa角鼻上方分布较多； 暗瞳时，左右眼Kappa角颞上分布较多。明暗瞳孔下，Kappa角的水平及垂直偏移的差异均有统计学意义(P<0.01)。

结论：不同明暗度下瞳孔大小的改变会影响Kappa角的大小，这种变化可能对依据Kappa角进行居中设计的角膜屈光手术的准确性产生影响。

METHODS:Two hundred and thirty-four eyes of 118 patients for corneal refractive surgery were enrolled for this study. Pupil diameters and angle Kappa values under light and dark conditions were measured by Keratron Scout corneal topography.

RESULTS: There were significant differences in pupil diameters between light and dark conditions(P<0.01). More angle Kappa of both eyes distributed in the superior nasal quadrant under light conditions, and more angle Kappa distributed in the superior temporal quadrant under dark conditions. The differences of horizontal and vertical offsets of angle Kappa under two conditions were statistically significant(P<0.01).

CONCLUSION: The changes of pupil diameters in light and dark conditions could affect angle Kappa and then affect the accuracy of corneal refractive surgery centered on angle Kappa.