加味四物颗粒辅助治疗痰瘀互结型视网膜静脉阻塞的疗效

Adjuvant effect of flavored Siwu granules for phlegm and blood stasis mutual junction retinal vein occlusion

摘要:

目的：评价加味四物颗粒在临床中辅助治疗痰瘀互结型视网膜静脉阻塞的疗效。

方法：将60例60眼患者随机分为治疗组和对照组，两组患者均使用视网膜激光光凝和玻璃体腔注药，而治疗组加用加味四物颗粒。分别统计治疗前及治疗后8wk患者视力、眼底改变、眼底血管荧光造影、中医临床证候疗效、血液流变学检查以及安全性评估。

结果：治疗组在治疗后第8wk有效率、视力改善、视网膜循环时间、全血低切黏度、中医症候总有效率等方面，与对照组有统计学差异(P<0.05)。

结论：加味四物颗粒辅助治疗痰瘀互结型视网膜静脉阻塞可改善患者视力，并减少眼部并发症。

Abstract:

AIM: To evaluate the effect of flavored Siwu granules in the clinical adjuvant treatment for phlegm and blood stasis mutual junction retinal vein occlusion.

METHODS: Sixty patients(60 eyes)were randomly divided into treatment group and control group, both with retinal laser photocoagulation and intravitreal injection of triamcinolone acetonide, but the treatment group used flavored siwu granules. Vision, fundus change, fundus fluorescein angiography, clinical syndrome of traditional Chinese medicine(TCM), hemorheology examination and safety assessment were evaluated before and 8wk after treatment.

RESULTS: At 8wk after treatment, there were differences on vision improvement, retinal circulation time, whole blood low shear viscosity and total efficient rate of clinical syndrome of TCM, compared with control group(P<0.05).

CONCLUSION:Flavored siwu granules adjuvant for phlegm and blood stasis mutual junction retinal vein occlusion can improve visual acuity and reduce the eye complications.