方法：随机选取97例176眼配戴角膜塑形镜的青少年近视患者，在戴镜前、戴镜后1d，1wk，1、3、6mo检查平均等效球镜度(spherical equivalent，SE)、裸眼视力(uncorrected visual acuity，UCVA)、矫正视力(best corrected visual acuity，BCVA)、角膜曲率及角膜中央厚度，对比分析检查结果。

结果：配戴角膜塑形镜后1d，1wk，1、3、6mo的SE下降，UCVA明显改善，与戴镜前比较差异具有统计学意义(P<0.05)，戴镜后BCVA与戴镜前比较差异无统计学意义(P>0.05)； 配戴角膜塑形镜后1d，1wk，1、3、6mo的角膜曲率与戴镜前比较差异具有统计学意义(P<0.05)； 中央角膜厚度1wk开始变薄，1、3、6mo的中央角膜厚度与戴镜前比较差异具有统计学意义(P<0.05)。

结论：角膜塑形镜能有效降低近视度，显著提高裸眼视力。

METHODS:Ninety-seven young patients(176 eyes)with myopia wearing orthokeratology were randomly selected. Spherical equivalent(SE), uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), corneal curvature and central corneal thickness were examined before, after wearing at 1d, 1wk, 1, 3 and 6mo. The results were compared and analyzed.

RESULTS:SE decreased and UCVA increased at 1d, 1wk, 1, 3 and 6mo after wearing orthokeratology, the difference was statistically significant(P<0.05)when compared with before wearing. The difference of BCVA after wearing orthokeratology compared with before has no statistics significant(P>0.05). The difference of corneal curvature after wearing orthokeratology for 1d, 1wk, 1, 3 and 6mo compared with before was statistically significant(P<0.05). The central corneal thickness became thiner after wearing orthokeratology for 1wk, and the central corneal thickness after wearing orthokeratology for 1, 3, 6mo compared with before was statistically significant(P<0.05).

CONCLUSION:Orthokeratology can effectively reduce the degree of myopia, and significantly improve the uncorrected visual acuity.