目的：了解德州市干眼症的流行病学特点，分析不同年龄、不同职业人群干眼症患病率的差别，寻找相关危险因素，为制定干眼症诊疗措施提供科学依据。

方法：对2011-02/2014-11在德州市疾病预防控制中心体检中心参加社会性体检的8 145名普通人群开展干眼症问卷调查和相关眼部检查。

结果：目标人群中干眼症患者1 803例，患病率为22.14%； 女性患病率高于男性，男女之间差异有统计学意义(χ²=45.12，P<0.01)； 干眼症随年龄升高呈上升趋势，5～20岁、21～40岁、41～60岁、61～72岁人群患病率分别为9.61%(109/1134)、22.84%(789/3455)、23.06%(433/1878)、28.13%(472/1678)，有统计学差异(χ²=95.76，P<0.01)； 女性5～20岁、41～60岁及61～72岁两类人群干眼症患病率显著高于同年龄组男性； 各职业患病率具有显著差异，离退休人员最高(27.48%)，有统计学差异(χ²=59.80，P<0.01)； 主诉症状排前三位的为眼部干涩感(30.40%)、视物模糊或视力波动(24.73%)、畏光(14.53%)； 多因素Logistic回归分析提示视频终端综合征、配戴角膜接触镜、滥用滴眼液、空气污染是干眼症的主要危险因素。

结论：德州市干眼症防治情况严峻，应掌握主要临床表现特点，及时明确诊断，并针对不同人群采取有针对性的健康教育和行为干预措施。

AIM:To analyze epidemiological characteristics of dry eye and the difference of prevalence in groups with different profession and ages to investigate the relevant risk factors so as to lay a scientific foundation for the diagnostics and treatment of dry eye.

METHODS:Dry eye questionnaire and ocular examination were conducted to 8 145 common persons participating in social physical examinations in Dezhou Center for Disease Control and Prevention from February 2011 to November 2014.

RESULTS:In the target population, 1 803 persons were suffering dry eye, accounting for 22.14%,the prevalence in female was higher than that in male,there was significant difference between genders(χ²=45.12,P<0.01). The prevalence was on the rise along with the age, specifically in 5-20, 21-40, 41-60 and 61-72 years old groups,it was 9.61%(109/1 134), 22.84%(789/3 455), 23.06%(433/1 878)and 28.13%(472/1 678)respectively(χ²=95.76,P<0.01). The prevalence in female was significantly higher than that in male in the 5-20, 41-60 and 61-72 years old groups. The prevalence varied significantly in different occupational populations,and the retiree accouted for the largest proportion(27.48%)(χ²=59.80,P<0.01); the top 3 main complaints were eye dryness(30.40%), blurred vision or vision fluctuation(24.73%)and photophobia(14.53%)in sequence; in addition, the multivariable Logistic regression analysis showed that visual display terminal syndrome, wearing corneal contact lens, the abuse of eye drops and air pollution were the main risk factors for the dry eye symptoms.

CONCLUSION:Dry eye prevention and treatment are badly in need in Dezhou city; and the major clinical characteristics of the disease should be grasped to make a timely and accurate diagnosis and to conduct specific health education and behavior interventional measures to people with different occupations.