方法：选取2012-05/2015-09在我院眼科治疗的特发性黄斑裂孔患者100例100眼，经玻璃体切割术后，比较治疗前后患者的最佳矫正视力(BCVA)和OCT检查参数的差异； 对术后BCVA与术前BCVA和OCT检查参数做Pearson相关分析和多元线性回归分析。

结果：患者治疗后视力检查BCVA值为0.357±0.172，高于治疗前(0.137±0.115)，差异具有统计学意义(P<0.05)； 治疗后OCT检查，基底直径、最小直径、裂孔高度、黄斑部视网膜厚度均低于治疗前，差异具有统计学意义(P<0.05)； Pearson相关分析结果显示：术后BCVA与基底直径(r=-0.397，P<0.01)和最小直径(r=-0.397，P<0.01)呈负相关； 术后BCVA与裂孔高度(r=0.399，P<0.01)、黄斑部视网膜厚度(r=0.345，P<0.01)、MHI(r=0.318，P=0.001)、HPF(r=0.417，P<0.01)呈正相关； 多元线性回归分析结果显示：术后BCVA与黄斑部视网膜厚度呈正相关(T=2.323，P=0.022)。

结论：玻璃体切割术治疗特发性黄斑裂孔效果良好，且术前OCT检查参数与术后视力恢复呈高度相关。

METHODS:One hundred cases(100 eyes)with idiopathic macular hole treated in our hospital from May 2012 to September 2015 underwent vitrectomy were selected. The differences before and after operations on best corrected visual acuity(BCVA)and OCT parameters were compared. Pearson correlation analysis and multiple linear regression analysis were performed on aforementioned parameters.

RESULTS:After treatment,the BCVA(0.357±0.172)was significantly higher than that before treatment(0.137±0.115)(P<0.05). The postoperative basal diameter, minimum diameter, the height of the hole, and the thickness of the retina were significantly lower than those preoperative(P<0.05). Pearson correlation analysis results showed:the postoperative BCVA was negatively correlated with basal diameter(r=-0.397,P<0.01)and minimum diameter(r=-0.397, P<0.01); the postoperative BCVA was positively correlated with the height of the hole(r=0.399,P<0.01), the thickness of the retina(r=0.345,P<0.01), MHI(r=0.318,P=0.001)and HPF(r=0.417, P<0.01). Multivariate linear regression analysis showed that the postoperative BCVA was positively correlated with macular retinal thickness(T=2.323,P=0.022).

CONCLUSION:Vitrectomy for idiopathic macular hole has good effect,and the parameters of OCT examination were highly correlated with the recovery of postoperative visual acuity.