方法：选取本院2014-10/2015-10收治的葡萄膜炎继发黄斑水肿患者68例82眼，并其按随机数字表法分为对照组和试验组，每组34例41眼患者。对照组患者采用经球内注射曲安奈德，试验组患者采用经结膜下注射曲安奈德。对比两组患者治疗后临床效果，黄斑中心凹视网膜厚度(CMT)变化，不良反应发生的情况。

结果：两组患者治疗前黄斑中心凹视网膜厚度及最佳矫正视力比较无统计学意义(P>0.05)； 但试验组治疗后黄斑中心凹视网膜厚度(214.26±65.54μm)明显低于对照组(256.47±84.52μm)； 试验组治疗后最佳矫正视力(4.8±1.3)明显优于对照组的(4.0±1.4)，差异具有统计学意义(P<0.05)； 试验组患者治疗后的总有效率(98%)明显高于对照组的(83%)，差异具有统计学意义(P<0.05)； 试验组患者治疗后不良反应的总发生率(37%)明显低于对照组的(59%)，差异具有统计学有意义(P<0.05)。

结论：葡萄膜炎继发黄斑水肿患者采用结膜下注射曲安奈德可以有效地改善患者视力及减轻黄斑水肿的情况，减少眼压升高、结膜出血等并发症发生。

METHODS:Sixty-eight patients(82 eyes)with macular edema secondary to uveitis selected in our hospital from October 2014 to October 2015 were assigned into control group and experimental group according to random number table method, with 34 cases(41 eyes)in each group. Patients in the control group were treated by intraocular injection of triamcinolone acetonide, and patients in the experimental group were given subconjunctival injection of triamcinolone acetonide. Clinical effect, central macular thickness and adverse reactions in the two groups were compared.

RESULTS:There was no significant difference on the central macular thickness and best corrected visual acuity between the two groups before treatment(P>0.05). Central macular thickness in the experimental group after treatment(214.26±65.54 μm)was significantly lower than that in the control group after treatment(256.47±84.52 μm,P<0.05), and best corrected visual acuity in the experimental group after treatment(4.8±1.3)was significantly higher than that in the control group(4.0±1.4, P<0.05). The overall response rate in the observation group(98%)was obviously higher than that in the control group(83%, P<0.05). The incidence of adverse reactions in the observation group(37%)was significantly lower than that in the control group after treatment(59%, P<0.05).

CONCLUSION:Subconjunctival injection of triamcinolone acetonide exerts obvious effect in uveitis patients with macular edema, effectively improves visual acuity, alleviates macular edema and reduces the incidence of intraocular pressure increasing, conjunctival hemorrhage and other adverse reactions, which is safe and effective, thus has potential application.