方法：急性闭角型青光眼行小梁切除患者60例68眼，按是否合并可调节缝线治疗随机分入两组，对照组为小梁切除组，观察组为小梁切除联合可调节缝线组，分别于术前及术后1、7、30、90d行泪膜破裂时间(tear break-up time，BUT)、泪液分泌试验(Schirmer Ⅰ test，SⅠt)、角膜荧光染色(fluorescent，FL)检查，同时观察术前和术后1、30d时的体征和症状。

结果：观察组术后7d内SⅠt值及术后3d时FL值均明显高于对照组(P<0.05)，术后30d起两组患者间SⅠt值及FL值无明显差异； 术后1d观察组的异物感、结膜充血及畏光感明显强于对照组(P<0.05)，术后30d起两组患者间无明显统计学差异(P>0.05)。

结论：小梁切除术中使用可调节缝线在短时间内会对术眼眼表泪膜产生不利影响，但拆除缝线后不利影响将很快消除。

METHODS:Sixty patients(68 eyes)with acute angle-closure glaucoma were divided into study group(trabeculectomy with adjustable suture)and control group(trabeculectomy without adjustable suture). The preoperative and postoperative data including tear break-up time(BUT), Schirmer I test(SⅠt), fluorescent(FL),and signs and symptoms of patients were analyzed respectively.

RESULTS:The results of SⅠt at 7d after surgery and FL at 3d after surgery in the study group were higher than those in the control group(P<0. 05). There were no significant differences on SⅠt and FL between the two groups since the thirtieth day after surgery. The signs of foreign body sensation, conjunctival congestion and photophobia at 1d after surgery in the study group were also higher than those in the control group(P<0.05); since the thirtieth day after surgery, there were no significant differences between two groups(P>0.05).

CONCLUSION:Using the adjustable suture in trabeculectomy will cause temporary impact on the tear film,and it will disappear soon after the suture being dismantled.