方法：选择本院常规体检的青少年为研究对象，采用铜卡法辨别屈光不正性弱视组的主视眼和非主视眼，各63例63眼； 正视眼者60例120眼为正常组。研究对象均采用散瞳并使用电脑验光联合带状检影镜检影，检查屈光度。对观察组主视眼和非主视眼配合适矫正眼镜，给予双眼同量综合弱视治疗。正常组不给予任何治疗。于同量综合弱视治疗后1、3、6、12mo末检查观察组和正常组矫正视力的疗效，并检测完全治疗后观察组和正常组分别在25、33、50cm距离处阅读过程中的调节微波动，每个注视距离检测5min。计算和分析调节微波动低频段(LFC)。随后采用i-Trace波前像差仪检测正视眼组和观察者研究对象全眼像差，用Humphrey角膜地形图仪采集和计算角膜像差，比较正常组和观察组调节微波动的差异，并分析调节指标与波前像差间的关系。

结果：经统计分析，观察组LFC值在25、33、50cm距离下分别为0.086±0.022、0.057±0.032、0.041±0.028D²/Hz，分别显著高于正常眼组在25、33、50cm距离下LFC值0.047±0.023、0.037±0.021、0.027±0.011D²/Hz，差异有统计学意义(P<0.05)。

结论：同量治疗下双眼屈光不正性弱视儿童短期内主视眼的疗效优于非主视眼，而中、长期疗效无明显差异。主视眼与非主视眼角膜像差无明显差异。在较近阅读距离下，调节微波动中的LFC能量弱视患者高于正视眼者。

METHODS:Teenagers who took routine physical examination were chosen as the research object. Copper card method was used to identify the dominant eye and the main eye in adolescents with ametropic amblyopia which was the observation group, 63 cases with 63 eyes each. Sixty subjects with emmetropia were as the normal group. The research objects underwent mydriasis optometry, computer optometry and streak retinoscopes to determine the diopter. The patients with ametropic amblyopia were treated with same amount comprehensive amblyopia treatment, and wearing glasses. There was not any treatment for normal group. The curative effect of same amount comprehensive amblyopia treatment were tested between the observation group and the control group when treating at 1,3,6 and 12mo respectively. Microfluctuation changes when reading at the distance of 25, 33 and 50cm(5min for every distance)of the two groups were tested. Then the low frequencies(LFC)of microfluctuation change was calculated and analyzed. The whole eye aberration of the normal group and the observation group were tested with i-Trace Wave Scan Wavefront, and the corneal aberration was collected and calculated with Humphrey corneal topographer. Microfluctuation changes of the two groups were compared and the relation between the accommodation index and the wavefront aberration was analyzed.

RESULTS:Through statistical analysis, the LFC value of the observation group at 25, 33 and 50cm respectively was 0.086±0.022, 0.057±0.032 and 0.041±0.028D²/Hz, which was significantly higher than the LFC value of the normal group which was 0.047±0.023,0.037±0.021,0.027±0.011D²/Hz(P<0.05).

CONCLUSION:Under the same amount treatment, the short-term curative effect of dominant eyes in children with ametropic amblyopia is superior to the non-dominant ones. While the differences of medium and long-term efficacy have no statistical significance. There is no difference on corneal aberration between dominant and non-dominant eyes. At near distance, the LFC of microfluctuation change was higher in amblyopia patients than that in normals.