方法：选取2011-01/2015-10我院收治入院的糖尿病白内障患者63例79眼为研究对象。所有患者均符合WHO所制定的糖尿病及白内障的相关诊断标准，并行超声乳化加人工晶状体植入术。术后1d采用汉密顿焦虑量表(HAMA)对所有患者进行心理评定，按照评定结果将患者分为两组，<14分为非焦虑组，共34例，≥14分为焦虑组，共29例。比较两组的干眼情况与炎症反应程度。

结果：术后第1d两组干眼症状得分情况未见统计学差异(P>0.05)，术后7d两组干眼症状得分情况存在统计学差异，焦虑组干眼症状重于非焦虑组(P<0.05)。术后3mo两组干眼症状得分情况未见统计学差异(P>0.05)。术后第1d两组患者的前房炎症反应程度相比未见统计学差异(P>0.05)，术后第7d两组炎症反应程度相比，焦虑组较非焦虑组更为严重，差异具有统计学意义(P<0.05)。术后3mo两组患者的前房炎症反应程度相比未见统计学差异(P>0.05)。术后第1d两组IL-1β、IL-6及TNF-α水平比较未见统计学差异(P>0.05)，术后第7d焦虑组的IL-1β、IL-6及TNF-α水平显著高于非焦虑组，差异具有统计学意义(P<0.05)。术后3mo两组IL-1β、IL-6及TNF-α水平比较未见统计学差异(P>0.05)。

结论：焦虑因素对于糖尿病合并白内障患者术后干眼症状与炎症反应程度具有显著影响，在术前进行焦虑评估，有针对性地制定心理干预措施，对于患者短时间内的术后恢复具有重要意义。

METHODS:Sixty-three diabetic patients(79 eyes)with cataract treated from January 2011 to October 2015 in our hospital were selected. All the patients were conformed to the WHO diagnosis standards of diabetes and cataract. The patients received the phacoemulsification and intraocular lens implantation. After 1d of treatment, Hamilton Anxiety Rating Scale(HAMA)was applied to evaluate the psychological state. According to the evaluation results, the patients were divided into non-anxiety group(<14 scores)and anxiety group(≥14 scores). The non-anxiety group had 34 cases and the anxiety group had 29 cases. The dry eye and inflammatory response of the two groups was compared.

RESULTS:At 1d and 3mo after treatment, the evaluation scores of dry eye of two groups were not significantly different(P>0.05); at 7d after treatment, the dry eye of anxiety group was more serious than that of non-anxiety group(P<0.05). At 1d and 3mo after treatment, the anterior chamber inflammation responses of two groups were not significantly different(P>0.05); at 7d after treatment, the inflammation response of anxiety group was more serious than that of non-anxiety group(P<0.05). At 1d and 3mo after treatment, the levels of IL-1β, IL-6 and TNF-α of the two groups were not significantly different(P>0.05); at 7d after treatment, the levels of IL-1β, IL-6 and TNF-α of anxiety group were significantly higher than those of non-anxiety group(P<0.05).

CONCLUSION: Anxiety has an obvious effect on the dry eye and inflammation response in diabetic patients after cataract surgery. Before surgery, the evaluation of anxiety and the targeted mental intervention is of great importance on the postoperative recovery.