方法：回顾分析于我院应用牛心包膜行后巩膜加固术的病理性近视患儿21例40眼，以同期未予手术治疗的病理性近视患儿13例26眼为对照组，随访3a，比较两组的屈光度、最佳矫正视力以及眼轴长度的变化情况。

结果：随访3a后治疗组的平均等效球镜度为-12.90±3.22D，对照组为-13.40±1.85D，两组平均等效球镜度分别增加-1.13±0.45、-1.93±0.44D，两组相比差异有显著统计学意义(P<0.01)； 最佳矫正视力分别增加0.25±0.11、0.16±0.07，两组相比差异有显著统计学意义(P<0.01)； 眼轴增长分别为0.71±0.34、1.18±0.40mm，两组相比差异有显著统计学意义(P<0.01)。术后无1眼出现视网膜脱离、眼前节缺血综合征、排斥反应、眼内出血等严重并发症。

结论：后巩膜加固术可以安全、有效地阻止青少年病理性近视的眼轴延长、控制近视进展，并能提高视功能。

METHODS:Forty eyes in 21 teenagers with pathological myopia who underwent the posterior scleral reinforcement using bovine pericardium(PSR group)were retrospectively studied, and at the same time 26 eyes in 13 age- and myopia-matched children who wore spectacles were analyzed as the control group. They were followed for 3a. The changes of best-corrected visual acuity, myopic diopter and axial length before and after treatments were measured and compared between the two groups.

RESULTS:The mean spherical equivalent degree after 3a in PSR group was -12.90±3.22D, and which in the control group was -13.40±1.85D. The mean spherical equivalent degree at the end of the follow-up period in the PSR group and the control group were increased by -1.13±0.45D and -1.93±0.44D respectively, and the difference between the two groups was statistically significant(P<0.01). The best-corrected visual acuity were increased by 0.25±0.11 and 0.16±0.07 respectively, and the difference between the two groups was statistically significant(P<0.01). The increase of axial length were 0.71±0.34 and 1.18±0.40mm respectively, and the difference between the two groups was statistically significant(P<0.01). There was no serious complication such as retinal detachment, anterior segment ischemia syndrome, rejection reaction and intraocular hemorrhage in the PSR group after the surgery.

CONCLUSION:Posterior scleral reinforcement surgery can not only effectively slow down high myopic axial progression and control the myopia development, but also elevate the visual acuity.