方法：回顾性研究。回顾分析我院在2004～2015年收治的327例诊断为恶性眼周肿瘤患者的病历资料。研究参数包括年龄、性别、患者所在城市、现病史(非肿瘤引起或与肿瘤相关的)、临床与病理诊断、肿瘤大小、位置及手术方式等。

结果：在327例患者中，46例(14.1%)患者诊断出患有突发恶性眼周肿瘤。男性与女性的患病比例为2：1。平均年龄为66.39±10.59(22-83)岁。最常见的临床疾病或症状为白内障致视觉模糊(44%)，其次为白内障合并其他相关症状类似泪溢症等(21.7%)。初步临床诊断联合病理诊断95.7%为皮肤癌。平均病变大小为1.04×0.85(0.2×0.2～3.0×3.0)mm²。肿瘤的最大直径和患者年龄无明显关系(P=0.105)。最常见的肿瘤位于下眼睑(30.4%)，其次为内眦处(26.1%)。随访时间6mo至3a(平均9.3mo)。

结论：突发恶性眼周肿瘤在本研究中较为常见，任何可疑病灶须尽快切除。一些患者忽视这些病变的原因需要进一步的前瞻性研究分析。

METHODS: Retrospective medical charts of 327 patients with malignant periocular tumor diagnosis at Jordan military hospitals between 2004 and 2015 were reviewed. Study variables included age, gender, city where patient lived, the presenting complaint(not caused by or related to tumor), clinical and histological diagnosis, size of the tumor, location, and surgical procedure.

RESULTS:A total of 327 charts reviewed, 46(14.1%)patients were found to have incidental malignant periocular tumor. Males where affected more than females with a ratio of 2:1. The average age was 66.39±10.59(22-83y). The most common presenting symptom or disease was blurring of vision secondary to cataract(44%), followed by combined cataract and other associated complaints such as epiphora in 21.7%.

Preliminary clinical diagnosis corresponded with histological diagnosis in 95.7% of skin cancer. The average size of the lesions was 1.04×0.85 mm²(0.2×0.2-3.0×3.0 mm²). There was no significant relationship between the maximum diameter of the tumor and age of the patient,(P=0.105). The most frequent location of tumors was the lower eyelid(30.4%)followed by the medial canthus(26.1%). The follow up period ranged between 6mo and 3y(average 9.3mo).

CONCLUSION: Incidental malignant periocular malignant tumors were relatively common in this study, which urges excision of any suspicious lesion particularly young patients. A prospective study is needed to investigate the reasons why some patients neglect these lesions.