[关键词]
[摘要]
目的：探讨飞秒激光准分子激光原位角膜磨镶术(laser
in situ keratomileusis，LASIK)与前弹力层下激光角膜磨镶术(sub-Browman's keratomileusis，SBK)术后干眼及泪膜功能的变化。
方法：回顾性分析2013-01/09在我院接受近视手术患者220例440眼。其中126例252眼为飞秒LASIK组，94例188眼为SBK组，分别观察两组术前及术后1wk，1、3、6mo的角膜荧光素染色(fluorescence staining，FL)、泪膜破裂时间(tear break-up time，BUT)、泪液分泌试验(SchirmerⅠtest，SⅠt)的变化。
结果：飞秒LASIK组和SBK组术后1wk和1mo荧光素染色评分，两组间比较差异有统计学意义(P<0.05)，术后3mo和6mo两组间比较差异无统计学意义(P>0.05)。术后1wk和1mo BUT，两组间比较差异有统计学意义(P<0.05)，术后3mo和6mo两组间比较差异无统计学意义(P>0.05)。术后1wk、1mo和3mo Schirmer Ⅰ试验两组间比较差异有统计学意义(P<0.05)，术后6mo两组间比较差异无统计学意义(P>0.05)。
结论：飞秒LASIK和SBK术后患者早期均有不同程度的干眼，但飞秒LASIK术后的泪膜功能恢复较SBK快。
[Key word]
[Abstract]
AIM:To evaluate the changes of postoperative dry eye and tear-film after femtosecond laser
in situ keratomileusis(femto LASIK)or sub-Bowman's keratomileusis(SBK).
METHODS:Two hundred and twenty patients(440 eyes)accepted the refractive surgery from January to September 2013 in our hospital were analyzed retrospectively. Two hundred and fifty-two eyes in 126 patients were performed with femto-LASIK, and 188 eyes in 94 cases were performed with SBK. The changes on corneal fluorescence staining(FL), tear film break-up time(BUT), and Schirmer Ⅰ test(SⅠt)were obtained preoperatively, 1, 3 and 6mo postoperatively.
RESULTS:There were significant difference between femo-LASIK and SBK on FL at 1mo postoperatively(P<0.05), and no significant differences at 3 and 6mo postoperatively(P>0.05). At 1wk and 1mo postoperatively, the differences on BUT between the two groups were statistically significant(P<0.05), and no significant differences at 3 and 6mo postoperatively(P>0.05). At 1wk,1 and 3mo postoperatively, the differences on SⅠt between the two groups were statistically significant(P<0.05). However, there was no significant difference at 6mo postoperatively on SⅠt between the two groups(P>0.05).
CONCLUSION:Both patients treated by femto-LASIK or SBK have dry eye after surgeries in early stage.However, tear-film function in femto-LASIK group recovers faster than that in SBK group.
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