[关键词]
[摘要]
目的:观察电针球后、合谷穴改善后天性单纯性外展神经麻痹眼球运动障碍的临床疗效。
方法:随机将首都医科大学附属北京中医医院眼科门诊2012-03/2015-03确诊为后天性单纯性外展神经麻痹的患者48例48眼,分为治疗组26例26眼和对照组22例22眼。治疗组采用电针患侧球后、合谷穴,配合体针加眼周诸穴; 对照组口服甲钴胺片(0.5mg,3次/d)加患侧颞浅静脉旁皮下注射复方樟柳碱注射液(1次/d,每日2mL)治疗。两组患者治疗期间均遮盖患眼,疗程1mo,观察患者眼球运动度的改善情况。
结果:两组治疗前基本情况经统计学分析具有可比性。经过1mo治疗后,电针球后、合谷穴治疗组眼球运动度改善明显,由治疗前13.06±2.31mm增加到治疗后19.35±3.21mm,明显优于对照组,两组比较差异有显著统计学意义(t=-5.43,P<0.01)。电针球后、合谷穴治疗组有效率为88.5%,对照组有效率为63.6%,两组比较差异有统计学意义(χ2=4.16,P=0.04)。
结论:电针球后、合谷穴对治疗后天单纯性外展神经麻痹所引起的眼球运动障碍具有一定疗效,值得进一步临床研究。
[Key word]
[Abstract]
AIM:To observe the clinical curative effect of electroacupuncture connecting Qiuhou(EX-HN7)and Hegu(LI-4)for eyeball movement disorder caused by acquired simplex abducens nerve palsy.
METHODS:Randomly we divided 48 cases(48 eyes)into treatment group(26 cases with 26 eyes)and control group(22 cases with 22 eyes), diagnosed with abducens nerve palsy from March 2012 to March 2015 at ophthalmology department of Beijing hospital of traditional Chinese medicine affiliated to Capital Medical University. Patients in treatment group were treated by electroacupuncture connecting Qiuhou(EX-HN7)and Hegu(LI-4), with body acupuncture and acupoints around eye. Control group took methylcobalamin(0.5mg, 3 times per day)orally and subcutaneously injection of compound anisodine hydrobromide by the superficial temporal vein(2mL, once a day)as the treatment. During the treatment, affected eyes of all the patients were covered. The course of treatments was 1mo. The improvement of eye movements was observed.
RESULTS:The date of the two groups was comparable at baseline. After 1mo treatments, the eye movement of treatment group was significantly improved from 13.06±2.31mm pre-treatment to 19.35±3.21mm post-treatment, than that of the control group. The difference was statistically significant(t=-5.43, P<0.01). The effective rate of the treatment group was 88.5%, higher than that of the control group(63.6%).The difference was statistically significant(χ2=4.16, P=0.04).
CONCLUSION:The electroacupuncture connecting Qiuhou(EX-HN7)and Hegu(LI-4)has certain effects on the treatment of eyeball movement disorder caused by simplex abduction paralysis. It is worth further clinical research.
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[基金项目]
北京市自然基金(No.7152071); 首都中医药专项(No.15ZY09)