不同白内障超声乳化术切口对糖尿病患者术后干眼的影响

Effect of different incision phacoemulsification on postoperative dry eye in diabetics

摘要:

目的：比较3.0mm和2.2mm两种白内障手术切口术后泪膜稳定性的变化。

方法：选取合并糖尿病的老年性白内障患者76例92眼，随机分组：A组48眼行3.0mm透明角膜切口白内障超声乳化术； B组44眼行2.2mm透明角膜切口白内障超声乳化术。观察术前及术后7d，1、3mo的干眼症状、基础泪液分泌、泪膜破裂时间及角膜荧光素染色情况。

结果：A组术后各时间点干眼症状明显重于B组，术后1wk，1mo角膜荧光染色检查明显多于B组，泪膜破裂时间明显低于B组，差异有统计学意义(P<0.05)，术后1mo时，A组基础泪液分泌高于B组，两组差异有统计学意义(P<0.05)。

结论：2.2mm切口较3.0mm切口在合并糖尿病的白内障患者超声乳化术后干眼症状更轻，持续时间更短。

Abstract:

AIM: To compare the changes of tear film stability after the combined surgery of phacoemulsification and intraocular lens(IOL)implantation through two different clear corneal incisions(3.0mm and 2.2mm).

METHODS: Preoperatively, 76 age-related cataract patients(92 eyes)with diabetes were divided into two groups. Forty-eight eyes were enrolled in group A, they were treated with 3.0mm clear corneal incision. And 44 eyes in group B were treated with 2.2mm clear corneal incision. Subjective score for dryness, Schirmer I test, tear film break-up time and corneal fluorescein staining were evaluated preoperatively and 7d, 1 and 3mo postoperatively.

RESULTS: Complains of dry eye and corneal fluoreascein staining was more severe in group A and tear film break-up time of group A was lower than that of group B with statistical difference(P<0.05)at postoperative 7d and 1mo. Schirmer Ⅰ test result of group A was higher than that of group B at postoperative 1mo with statistical difference(P<0.05).

CONCLUSION: Compared with 2.2mm group(group B), the symptom of dry eye was slighter and the duration was shorter than 3.3mm group(group A)after phacoemulsification in cataract patients with diabetes.