方法：选择2014-09-15/12-31本院集中收治的高度近视合并白内障患者86例86眼，随机分为两组：A组46例46眼行白内障超声乳化术； B组40例40眼行小切口白内障囊外摘除术。于术前1d及术后7d，1、3mo时观察两组患者视力及角膜内皮细胞密度和六角形细胞的比例。

结果：两组患者术后视力较术前均显著改善(P<0.05)，组间比较无显著性差异(P>0.05)； 两组患者角膜内皮细胞密度和六角形细胞比例术后7d，1、3mo较术前均下降，差异有统计学意义(P<0.05)，组间比较无显著性差异(P>0.05)。

结论：白内障超声乳化术和小切口白内障囊外摘除术两种术式对高度近视合并白内障患者角膜内皮细胞均有一定程度损伤，患者术后视力均有明显改善，疗效相当。

METHODS: In the study, 86 patients(86 eyes)with high mypia combined with cataract from September 15^th, 2014 to December 31^th, 2014 were selected and randomly divided into two groups, group A(46 cases, 46 eyes)with phacoemulsification and group B(40 cases, 40 eyes)with extracapsular cataract extraction with small incision. Visual acuity, the density of corneal endothelial cells and the proportion of hexagonal cells were observed at preoperative 1d and postoperative 7d, 1 and 3mo.

RESULTS: After treatment, visual acuity was improved significantly in both groups(P<0.05), with no statistical difference between two groups(P>0.05). Compared with preoperative 1d, there were significant differences for the density of corneal endothelial cells and the proportion of hexagonal cells at postoperative 7d, 1 and 3mo(P<0.05), but with no statistical difference between two groups(P>0.05).

CONCLUSION: Phacoemulsification and extracapsular extraction with small incision have a certain extent damage on corneal endothelial cells in patients with high mypia and cataract. However, both two surgical approaches show equivalent efficacy in improving visual acuity of patients with high mypia combined with cataract.