方法：选取经MSICS治疗的306眼老年性白内障患者和经超声乳化(Phaco组)治疗的306眼老年性白内障患者，对两组患者的术后视力、屈光状态、角膜内皮细胞损失率进行比较。

结果：MSICS组术后7d裸眼视力在1.0以上者33眼(10.78%)； 术后3mo裸眼视力在1.0以上者76眼(24.84%)，角膜内皮细胞损失率为8.7%，角膜散光较术前平均逆规化0.75D。Phaco组术后7d裸眼视力在1.0以上者63眼(20.59%)； 术后3mo裸眼视力在1.0以上者92眼(30.07%)，角膜内皮细胞损失率为21.67%。MSICS组平均角膜散光为-0.5DC，Phaco组平均角膜散光为-0.45DC，3mo时两组角膜散光无统计学差异(P>0.05)。

结论：Phaco组因要使用超乳机，成本高，且超乳头的机械刺激、损伤、超声能量及灌注液对角膜内皮的影响，术后早期视力恢复慢。MSICS不使用超声乳化仪、手工作、成本低、术后早期视力恢复快。

METHODS: Three hundred and six eyes age-related cataract were taken MSICS and 306 eyes received phacoemulsification(Phaco group). Visual acuity, the refractive and the loss ratio of cornea endothelia cells were observed and compared after surgery.

RESULTS: Uncorrected visual acuity of 33 eyes(10.78%)and 76 eyes(24.84%)was >1.0 in 7d and 3mo after MSICS. The loss ratio of cornea endothelia cells was 8.7%, The recursive of corneal astigmatism was on average 0.75D compared with preoperation. Uncorrected visual acuity of 63 eyes(20.59%)and 92 eyes(30.07%)was >1.0 in 7d and 3mo after phacoemulsification. The loss ratio of cornea endothelia cells was 21.67%. The average corneal astigmatism was -0.5DC and -0.45DC in MSICS group and Phaco group respectively, but 3mo after surgery, there was no significant difference on corneal astigmatism between the two groups(P>0.05).

CONCLUSION: Due to the use of Phaco machine, the cost is higher in Phaco group, and the Phaco mechanical stimulation, injury, ultrasonic energy and perfusion solutions have effects on corneal endothelium, visual acuity recovery at early postoperative is slow. However, MSICS dose not use Phaco machine, works by hands, the cost is lower, and visual acuity recovery at early postoperative is faster.