[关键词]
[摘要]
葡萄膜炎是一类严重损害视功能的炎症性疾病。葡萄膜炎发病机制尚不清楚，感染、外伤、肿瘤、自身免疫反应均可引起，以自身免疫反应引起者最为常见。近年来，细胞因子在自身免疫性疾病的炎症过程中所起作用成为研究热点之一，其在发病机制中的作用与疾病活动之间的关系越来越被关注，我们就干扰素、肿瘤坏死因子、白细胞介素、转化生长因子等与葡萄膜炎发病密切相关的细胞因子作一综述。
[Key word]
[Abstract]
Uveitis is a group of inflammatory diseases causing serious impairment of visual function. The precise etiology and pathogenesis remain unclear. It can be induced by infection, trauma, tumor or autoimmune response, of which autoimmune response is the most common. In recent years, the cytokines in the process of inflammatory autoimmune diseases role has become one of research hot spots, its role in the pathogenesis and the relationship between the disease activity more and more attention. This article reviews the effects of interleukin, tumor necrosis factor, interferon and transforming growth factor-β in the pathogenesis of uveitis.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81271026); 福建省自然科学基金资助项目(No.2012J01344)
