[关键词]
[摘要]
目的:探讨血栓通联合羟苯磺酸钙应用于糖尿病视网膜病变导致的视野缺损的临床疗效。
方法:选取我院收治的糖尿病视网膜病变患者64例作为研究对象,将其随机均分为观察组和对照组,对照组采用血栓通进行治疗,观察组在上述治疗的基础上加用羟苯磺酸钙进行联合治疗。治疗5mo后,比较两组糖尿病视网膜病变患者的临床疗效,治疗前后视野、荧光造影及眼底照相变化情况,观察患者的不良反应及复发情况。
结果:两组患者的病情均明显好转,且观察组患者治疗有效率为97%,高于对照组的78%,差异比较有统计学意义(P<0.05); 观察组患者出血斑明显降低治疗前后比较有显著性差异,具有统计学意义(P<0.05),观察组的视野灰度值、出血斑、血管瘤变化情况均明显优于对照组,具有统计学意义。观察组患者未出现不良反应,且复发率明显少于对照组,复发率比较有显著性差异(P<0.05)。
结论:血栓通联合羟苯磺酸钙对糖尿病视网膜病变患者进行治疗,取得了比较满意的疗效,可以有效降低复发率,减少不良反应,显著改善临床症状,可在临床上推广应用。
[Key word]
[Abstract]
AIM: To research the clinical curative effect of Xueshuantong combined with calcium dobesilate on visual field defect caused by diabetic retinopathy.
METHODS: Sixty-four cases with diabetic retinopathy treated in our hospital patients were selected as the research objects. They were randomly divided into observation group and control group. The control group was treated with Xueshuantong, and the observation group was treated with combined treatment of calcium dobesilate. After 5mo, the clinical efficacy was compared between the two groups of diabetic retinopathy, and before and after treatment fundus photography, fluorescein angiography and visual field changes, observation of patients with adverse reactions and recurrence were performed.
RESULTS: The condition of patients was improved, and the effective rate of treatment group was 97%, and higher than that of the control group 78%, the differences were statistically significant(P<0.05); the patients in the observation group were significantly reduced bleeding spot, before and after treatment were significant difference, with statistical significance(P<0.05), field of vision gray, hemorrhage spots, and hemangioma changes in obsenartion group were significantly better than that of the control group, with statistical significance(P<0.05). In observation group, patients had no adverse reaction, and the recurrence rate was significantly less than the control group, and the recurrence rate were significant difference(P<0.05).
CONCLUSION: The patients with diabetic retinopathy treated with Xueshuantong combined with calcium dobesilate achieve satisfactory effect, and it can effectively reduce the recurrence rate and the adverse reactions, and improve the clinical symptoms. It would be widely applied in clinical practice.
[中图分类号]
[基金项目]
湖南省卫生厅科研基金项目(No.B2010103)