目的：探讨年龄相关性白内障患者角膜球面像差的分布情况及其影响因素，旨在为非球面人工晶状体在白内障患者术中应用提供科学的理论依据。

方法：回顾性研究在我院眼科住院的年龄相关性白内障患者509例610眼，iTrace视觉功能分析仪检查角膜球面像差、角膜曲率、角膜散光及角膜Q值，采用SPSS 16.0统计软件进行统计学分析。

结果：角膜球面像差波动范围为0～1.800μm； 角膜球面像差平均值为0.266±0.010μm； 角膜球面像差与年龄、角膜曲率及角膜散光无明显相关性(r=0.71，0.56，0.93，P>0.05)； 角膜球面像差与Q值呈正相关(r=0.086，P=0.03)。

结论：年龄相关性白内障患者角膜球面像差存在明显的个体化差异，在选择消除角膜正球差的非球面人工晶状体时，要根据患者的个体差异来做出个性化的选择。

AIM: To investigate the distribution and related factors of corneal spherical aberration in the age-related cataract patients, and to provide a scientific basis for the application of aspheric intraocular lens(IOL)in cataract surgery patients.

METHODS: Retrospective study of 509 age-related cataract patients of 610 eyes in our hospital. Corneal spherical aberration, corneal curvature, corneal astigmatism and corneal Q-value were examined by iTrace visual function analysis. Statistical software SPSS16.0 was used to analyze statistically.

RESULTS: The range of corneal spherical aberration was 0～1.800μm. The mean coefficient of corneal spherical aberration was 0.266±0.010μm. Corneal spherical aberration was no significantly correlation with age, corneal curvature, corneal astigmatism(r=0.71, 0.56, 0.93, P>0.05). There was positive correlation between corneal spherical aberration and Q-value(r=0.086, P=0.03).

CONCLUSION: Corneal spherical aberration varied greatly among age-related cataract patients. The choice of asphericity intraocular lens should be a matter of personal choice.