[关键词]
[摘要]
术中和术后预防、抑制纤维瘢痕形成是改善青光眼滤过手术降眼压治疗的重要手段。我们着重介绍目前用于和未来可能用于青光眼滤过术后伤口愈合调节的手段，主要包括各类药物(抗代谢药物、抗炎症药物、抗生长因子药物、作用于细胞信号通路的药物等)、新型给药系统等技术，以及这一领域今后的研究方向。
[Key word]
[Abstract]
To improve the effect of glaucoma filtration operation in reducing intraocular pressure(IOP), it's important to prevent and inhibit fibrotic scar formation during and after operation. This paper focuses on the current and future possible means for modulation of wound healing after glaucoma filtration surgery, mainly including series of medications(antimetabolites, anti-inflammation drugs, antigrowth factor drugs, drugs acting on cell signal pathways, etc.), new drug delivery system and other technologies. This article also discusses the future orientation in this field.
[中图分类号]
[基金项目]
国家科技支撑计划项目子课题(No.2012BAI08B01)
