方法：总结分析我院2011-01/2013-05施行超声乳化白内障吸除术的137例185眼和中切口白内障囊外摘除术的139例185眼患者资料，观察比较术中后囊膜破裂，术后视力，角膜水肿，角膜散光，眼压等情况。

结果：术后第1d，视力恢复中切口组高于超声乳化组，术后第3d； 1，3mo视力恢复两组无统计学意义； 术后第1d角膜水肿情况超声乳化组(45眼)高于中切口组(20眼)，差异有统计学意义(χ²=11.665，P=0.0006)； 两组病例术中后囊膜破裂无显著差异(χ²=0.094，P=0.759)。采用矢量分析法计算术后1wk； 1，3mo平均性手术诱发性角膜散光，在术后各时间点两组术式诱发性角膜散光度数有显著性差异(u=6.661，6.880，4.187，均P=0.00)。术前、术后1d； 1wk； 1，3mo不同时间点，两组患者之间眼压无显著性差异(u=1.858，0.963，0.471，1.349，1.388； P=0.063，0.335，0.638，0.177，0.165)。而囊外摘除组与超声乳化组，术后第1d较术前眼压均升高，有显著差异(u=19.86，19.39； 均P=0.00)，此后1wk； 1，3mo，术眼眼压较术前均有显著性降低，降压幅度大约为2～3mmHg，两组眼压变化趋势相同。

结论：超声乳化白内障吸除术与中切口白内障囊外摘除术均能有效治疗白内障，两组患者术后视力相当，对眼压的影响无明显差异，且两组均无严重并发症发生，但由于中切口白内障囊外摘除术具有操作简便、恢复快、仪器价格低廉等优势，且基层医院大规模防盲手术对象大部分为硬核白内障，结合当地基层医院和医生的实际情况，中切口白内障囊外摘除术安全、有效、易于操作，更适宜对高龄硬核白内障患者开展大规模防盲手术。

METHODS: One hundred and eighty-five eyes of phacoemulsification(137 cases)and 185 eyes of 139 cases for MI-ECCE from January 2011 to May 2013 were involved in this study. And the ratio posterior capsular rupture during surgery, visual acuity, corneal edema, corneal astigmatism and intraocular pressure post operation were followed up.

RESULTS: On 1d after surgery, uncorrected visual acuity in the group of MI-ECCE was better than that of phacoemulsification group, while from 3d; 1 and 3mo after surgery, no significant difference was found from the above two groups. On 1d postoperation, corneal edema ratio in phacoemulsification group(45 eyes)was higher than that in MI-ECCE group(20 eyes)(χ²=11.665, P=0.0006). No significant difference was found for the ratio of posterior capsule rupture during surgery in these two surgical technique groups(χ²=0.094,P=0.759). On 1wk; 1 and 3mo after surgery, significant difference was found for the average of surgical induced corneal astigmatism between two groups(u=6.661, 6.880, 4.187, P=0.00, respectively). During following up, no significant difference was found for the intraocular pressure between two groups(u=1.858, 0.963, 0.471, 1.349, 1.388; P=0.063, 0.335, 0.638, 0.177, 0.165). Intraocular pressure on 1d postoperation in phacoemulsification and MI-ECCE groups was higher than before operation(u=19.86, 19.39, P=0.00, respectively). And on 1wk; 1 and 3mo postoperation, intraocular pressure in the operated eyes in both groups was lower than before operation for 2～3mmHg.

CONCLUSION: Although phacoemulsification and MI-ECCE could both get good visual rehabilitation, with similar visual outcome, no significant effect for intraocular pressure, and no severe complications, the latter one owns the advantage that easier maneuver, quicker recovery, and cheaper instruments needed, which is suitable for the hard nuclei cataract in local hospitals. MI-ECCE is a safe, effective and easy manipulation for local hospital for large batch of cataract surgeries.