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[摘要]
目的:研究翼状胬肉切除联合角膜缘干细胞移植术对患者视力和屈光状态的影响。
方法:将2012-03/2014-05期间我院收治的翼状胬肉患者120例178眼纳入研究对象,根据治疗方法不同分为观察组60例90眼和对照组60例88眼,观察组患者接受翼状胬肉切除联合角膜缘干细胞移植术治疗,对照组患者接受翼状胬肉切除术治疗,比较两组患者的视力水平、散光程度,分析年龄因素、工作环境以及内直肌止端距角膜缘距离对术后视力恢复情况的影响。
结果:术前两组患者的视力水平、散光程度无差异(P>0.05); 术后1,2,3,4wk时,观察组患眼视力高于对照组(0.49±0.09 vs 0.34±0.07, 0.76±0.11 vs 0.42±0.04, 0.95±0.14 vs 0.59±0.08, 1.09±0.18 vs 0.74±0.10),散光程度低于对照组(0.96±0.12 vs 1.85±0.28, 0.68±0.08 vs 1.51±0.23, 0.54±0.08 vs 1.23±0.19, 0.42±0.07 vs 0.91±0.14); 年龄≥45岁、室内工作、内直肌止端距角膜缘距离3~5 mm患者的视力水平更高、散光程度更低。
结论:翼状胬肉切除术联合角膜缘干细胞移植术治疗有助于改善视力水平和散光程度,且术后视力恢复情况受到年龄因素、工作环境以及内直肌止端距角膜缘距离的影响。
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[Abstract]
AIM: To study the effect of pterygium excision combined with limbal stem cell on visual acuity and refractive status.
METHODS:A total of 120 cases(178 eyes)pterygium cases were enrolled in our hospital from March 2012 to May 2014 and divided into observation group(60 cases, 90 eyes)and control group(60 cases, 88 eyes)according to different treatment methods. Patients in observation group received pterygium excision combined with limbal stem cell transplantation, those in control group received pterygium excision. Vision levels, astigmatism degrees were compared. The effects of age, working environment and medial rectus muscle insertion distance from corneal limbus on postoperative visual acuity were analyzed.
RESULTS:Before operation, acuity levels and astigmatism degrees of two groups had no difference(P>0.05); 1, 2, 3, 4wk after operation, visual acuity in observation group were higher than that in control group(0.49±0.09 vs 0.34±0.07, 0.76±0.11 vs 0.42±0.04, 0.95±0.14 vs 0.59±0.08, 1.09±0.18 vs 0.74±0.10), astigmatism degrees were lower than that in control group(0.96±0.12 vs 1.85±0.28, 0.68±0.08 vs 1.51±0.23, 0.54±0.08 vs 1.23±0.19, 0.42±0.07 vs 0.91±0.14); visual acuity of patients older than 45 years old, indoor work, medial rectus muscle insertion distance from corneal limbus 3-5 mm were higher, astigmatism degrees were lower.
CONCLUSION:Pterygium excision combined with limbal stem cell transplantation is helpful to improve visual acuity and astigmatism degree; recovery of visual acuity is affected by age, working environment and medial rectus muscle insertion distance from corneal limbus.
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