方法：将本院收治的80例96眼翼状胬肉患者分为高浓度组、低浓度组、对照组，3组患者均给予翼状胬肉切除联合自体角膜缘干细胞移植，高浓度组、低浓度组在干细胞移植前分别给予0.2，0.1mg/mL丝裂霉素C棉片覆盖。比较3组患者的愈合和复发情况，以及治疗前后裸眼视力。

结果：治疗前3组患者裸眼视力均无显著差异(P>0.05)，3组患者治疗后裸眼视力均得到显著改善(P<0.05)； 高浓度组上皮愈合时间显著高于低浓度组和对照组(P<0.05)，低浓度组和对照组上皮愈合时间无显著差异(P>0.05)； 低浓度组治愈率高于高浓度组，复发率低于高浓度组。

结论：翼状胬肉切除联合自体角膜缘干细胞移植对于翼状胬肉疗效确切，联合丝裂霉素C能够有效降低复发率，但对于合并T2DM患者应当降低丝裂霉素C浓度。

METHODS: Eighty patients of 96 pterygium eyes admitted to hospital were divided into groups of high concentration, low concentration group and the control group, and 3 groups were given pterygium excision combined with limbal stem cell transplantation. The high concentration group, the low concentration groups were given prior to stem cell transplantation 0.2, 0.1mg/mL mitomycin C coverage. The cure rate and recurrence rate in three groups of patients, as well as visual acuity before and after treatment were compared.

RESULTS: Three groups patients' visual acuity were significantly improved after treatment(P<0.05), there was no significant difference before treatment in visual acuity(P>0.05); epithelial healing time of high concentration group was significantly higher than low concentration group and the control group(P<0.05), there was no significant difference between low concentration and control groups of epithelial healing time(P>0.05); cure rates of low concentration group was higher than high dose group, the recurrence rate in low concentration group was lower than the high dose group.

CONCLUSION: Pterygium excision combined with limbal stem cell transplantation has significant efficacy for pterygium, and mitomycin C can effectively reduce the relapse rate, but for the patients with T2DM concentration of mitomycin C should be reduced.