方法：采用FS200飞秒激光系统制作个性化角膜瓣815例1 620眼，术中测量角膜瓣厚度，观察总结术中及术后角膜瓣的并发症。

结果：术后1d； 1wk达到或超过最佳矫正视力分别占总数98.16%和100%； 术后1d； 1wk等效球镜度数±0.50D内分别占总数97.55%和98.16%； 术后1d； 1wk等效球镜度数±1.00D内分别占总数99.39%和100%； 术中测量实际角膜瓣厚度值与预设值有统计学差异(P<0.05)； 发生球结膜下出血70例80眼(4.94%)，角膜瓣下气泡40例40眼(2.47%)，前房气泡2例2眼(0.12%)，隧道出血20例40眼(2.47%)，角膜瓣出血1例2眼(0.12%)，瓣边缘小片未切区3例3眼(0.19%)，边切较不规整及偏位10例10眼(0.62%)，负压环脱环1例1眼(0.06%)，改期手术7例8眼(0.49%)。

结论：FS200飞秒激光制瓣安全性高、舒适度好、并发症少。术者操作技术熟练、患者角膜上皮正常及配合度好情况下，FS200飞秒激光可制作薄至90μm的角膜瓣。

METHODS: A total of 1 620 eyes of 815 patients underwent LASIK with flaps created by wavelight FS200 femtosecond laser were involved. Corneal flaps thickness in operation was measured, the intraoperative and postoperative complications were observed and summarized.

RESULTS: 98.16% the uncorrected visual acuity(UCVA)postoperation 1d and 100% the UCVA postoperation 1wk reached the best corrected visual acuity preoperation or above; 97.55% of spherical equivalent refractions postoperation 1d and 98.16% of spherical equivalent refractions postoperation 1wk were within ±0.50D; 99.39% of spherical equivalent refractions postoperation 1d and 100% of spherical equivalent refractions postoperation 1wk were within ±1.00D; There were difference of corneal flaps thickness between measured value and preset value(P<0.05); 80 eyes of 70 patients had subconjunctival hemorrhage(4.94%), 40 eyes of 40 patients had bubbles under flap(2.47%), 2 eyes of 2 patients had anterior chamber bubbles(0.12%), 40 eyes of 20 patients bleed in canal(2.47%), 2 eyes of 1 patient bleed in corneal margin(0.12%), 3 eyes of 3 patients had flaps with an marginal uncut area(0.19%), 10 eyes of 10 patients had flaps with an irregular and dislocated margin(0.62%), 1 eye of 1 patient had suction loss during the operation(0.06%), 8 eyes of 7 patients postponed operation(0.49%).

CONCLUSION: FS200 femtosecond laser is safe, comfortable and little complications in the production of LASIK flaps. If the surgeon operate expertly, patients cooperate well and have healthy cornea epithelium, FS200 femtosecond laser can make ultra-thin corneal flap of 90μm safely.