方法：选取2013-01/12来我院激光治疗中心进行近视矫正的患者76例152眼，所有患者先后采用综合验光仪(NIDEK， RT-5 100)进行主觉验光，WaveScan(AMO Company，USA)和OPD-Scan Ⅲ像差仪(Nidek Technologies，Japan)进行客观验光检查。对这三种方法验光结果的球镜、柱镜及轴位进行统计学分析与比较。

结果：WaveScan验光的球镜度数较主觉验光结果偏低，差值0.13±0.30D(t=3.753， P<0.001)，柱镜结果偏高0.13±0.43D(t=3.664， P<0.001)。OPD-Scan Ⅲ与主觉验光球镜、柱镜及等效球镜之间的差异均无统计学意义(P>0.05)。WaveScan与主觉验光轴位度数平均相差5.87°±6.19°，OPD-ScanⅢ与主觉验光平均相差3.82°±3.95°，两者之间的差异有统计学意义(t=2.817，P=0.006)。

结论：WaveScan与主觉验光球镜及柱镜结果之间有差异，OPD-Scan Ⅲ作为最新的综合设备，在验光度数上有较高的准确性。

METHODS: Seventy-six patients(152 eyes)were recruited from January 2013 to December 2013. All patients were measured with subjective refraction by the phoropter(NIDEK, RT-5 100), objective refraction by the WaveScan(AMO Company, USA), OPD-Scan Ⅲ(Nidek Technologies, Japan). The sphere, cylinder, axis of the three methods were compared and analyzed.

RESULTS: The sphere measured by WaveScan was lower than that by subjective refraction, the difference was 0.13±0.30D(t=3.753, P<0.001). For cylinder, the difference was 0.13±0.43D(t=3.664, P<0.001). There was no significance for sphere, cylinder, and spherical equivalent between OPD-Scan Ⅲ and subjective refraction(P>0.05). The value of the difference between WaveScan and subjective refraction was 5.87°±6.19° for the axis and the difference between OPD-Scan Ⅲ and subjective refraction was 3.82°±3.95°. There was statistic significance(t=2.817, P=0.006).

CONCLUSION: For sphere and cylinder,WaveScan generated some deviation relative to subjective refraction. The Nidek OPD-Scan Ⅲ gives more accurate measures of objective refraction when compared with subjective refraction.