方法：选择我院2009-07/2013-11间收治的150例150眼黄斑水肿患者，按照数字随机法分为研究组(75例75眼)与对照组(75例75眼)，对照组患者采用黄斑格栅样光凝治疗，研究组采用曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗，分别于治疗前，治疗后7d； 1，3，9mo检测患者最佳矫正视力，并行光学相干断层扫描(optical coherence tomography，OCT)和荧光素眼底血管造影(fundus fluorescein angiography，FFA)检测。

结果：治疗后两组患者视力均明显改善(P<0.05)，研究组术后7d； 1，3，9mo的视力改善情况明显优于对照组及手术前(P<0.05)； 研究组术后7d； 1，3，9mo时视网膜黄斑中心凹神经上皮层厚度显著降低(P<0.05)，对照组术后7d； 1，3，9mo与治疗前相比视网膜黄斑中心神经上皮层厚度无统计学意义(P>0.05)，研究组黄斑中心凹视网膜神经上皮层厚度显著低于对照组(P<0.05)； 研究组出现7例眼压轻度增高，经降眼压治疗后均恢复正常。

结论：曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗黄斑水肿的临床疗效确切，可以有效提高患者视力，降低黄斑水肿症状，安全可靠，适于临床推广与应用。

METHODS: Totally 150 cases(150 eyes)with macular edema in our hospital from July 2009 to November 2013 were selected, which were randomly divided into study group(75 cases, 75 eyes)and control group(75 cases, 75 eyes). The cases in control group were treated with macular grid photocoagulation treatment, those in the study group used triamcinolone acetonide combined macular grid photocoagulation treatment. Best corrected visual acuity(BCVA), parallel optical coherence tomography(OCT)and fundus fluorescein angiography(FFA)were detected before treatment, after treatment 7d, 1, 3, and 9mo.

RESULTS:After the treatment, patients' vision were significantly improved in two groups(P<0.05). In the study group 7d, 1, 3, and 9mo after operation, the visual acuity was better than the control group and preoperative(P<0.05); fovea macular neurosensory layer thickness decreased significantly(P<0.05). In the control group, the point omentum macular neurosensory retinal thickness was not statistically significant at 7d, 1, 3, and 9mo after operation compared with before treatment(P>0.05). Fovea macular neurosensory retinal thickness in the study group was significantly lower than that in control group(P<0.05). Intraocular pressure of 7 cases in the study group increased slightly, and were normal after treatment.

CONCLUSION: Triamcinolone acetonide combined macular grid photocoagulation treatment is accurate, can effectively improve the visual acuity, reduce macular edema, it is safe and reliable, and suitable for clinical application.