[关键词]
[摘要]
目的:观察白内障超声乳化联合房角分离术治疗小梁切除术后绝对期青光眼的效果。
方法:对16例16眼绝对期青光眼施行白内障超声乳化联合房角分离术,随访6~12mo,观察眼压、前房深度、术前术后用药种类(数量)、术前与术后1mo焦虑和抑郁状态、眼表症状等情况。
结果:行白内障超声乳化联合房角分离术后,眼压明显下降。术前眼压平均值35.00±15.43mmHg,术后第1d眼压平均值为12.00±6.69mmHg; 术后6mo为15.00±4.26mmHg; 术后12mo为15.3±5.2mmHg。术后眼压与术前比较差异有统计学意义(t=6.22,P<0.05)。术前前房深度为1.45±0.19mm,术后增加至3.37±0.13mm,差异有统计学意义(t=6.65,P<0.05)。术后仅2例患者需用2种降眼压药物,2例患者需1种降眼压药物。术后12mo 16例患者的焦虑和抑郁状态均有所改善; 16例患者眼胀、眼痛等主观不适症状均减轻; 所有患者眼球都得以保留,且无严重并发症。
结论:超声乳化联合房角分离治疗小梁切除术后绝对期青光眼是安全、有效的手术选择。
[Key word]
[Abstract]
AIM: To observe the effect of phacoemulsification combined goniosynechialysis in treating absolute glaucoma after trabeculectomy.
METHODS: Phacoemulsification combined goniosynechialysis was performed on 16 patients(16 eyes)with absolute glaucoma after trabeculectomy, and they were followed up for 6~12mo, The postoperative intraocular pressure(IOP)and anterior chamber depth, preoperative and postoperative medication types(quantity), preoperative and postoperative 1 month's status of anxiety and depression, symptoms of ocular surface were observed.
RESULTS: The IOP decreased significantly after phacoemulsification combined goniosynechialysis. The mean IOP was 35.00±15.43mmHg preoperatively, and it was 12.00±6.69mmHg, 15.00±4.26mmHg and 15.3±5.2mmHg on 1d, 6 and 12mo after the surgery. The statistic difference was found between preoperative and postoperative(t=6.22, P<0.05). The anterior chamber depth was 1.45±0.19mm before the surgery, and increased to 3.37±0.13mm after the surgery(t=6.65, P<0.05). After the surgery, 2 patients needed two kinds of drugs, 2 patients needed one kind of drug. After 12mo of follow-up, anxiety and depression status were improved in all 16 patients. Subjective discomfort symptoms of 16 patients such as eye bilges, eye pain were relieved. All of the patients' eyeballs were preserved, and no serious complications.
CONCLUSION: Phacoemulsification combined goniosynechialysis in treating absolute glaucoma after trabeculectomy is a safe and effective surgical option.
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[基金项目]
国家自然科学基金项目(No.81400372,81160118); 全国临床医药专项基金(No.L2012052); 江西省科技支撑计划项目(No.20111BBG700262); 江西省自然(青年)科学基金(No.20114BAB215036); 江西省科技平台建设项目(No.2013116); 江西省教育厅青年科学基金项目(No.JJJ12158); 江西省卫生厅科技计划面上项目(No.20121026); 江西省卫生厅中医院科研项目(No.2012A087)