方法：回顾性病例分析研究。选取2013-03/11在我院行改良23G免缝合微切口玻璃体切除手术的98例98眼纳入研究。采用非接触式眼压计测量眼压在25mmHg以上的术眼临床资料进行分析。连续监测手术后7d的眼压情况，分析患者年龄、性别、眼别、病程及手术前原发疾病、眼内手术史、手术方式、不同眼内填充物、晶状体状态及手术时间对手术后高眼压发生的影响。

结果：23G玻璃体切除术后7d内共33眼出现高眼压，发生率是33.7%(33/98)，其中，发生在术后第1d者8眼，占24.2%(8/33)，术后3d者25眼，占75.8%(25/33)。男、女高眼压的发生率分别为32.8%(20/61)和35.1%(13/37)，右、左眼高眼压发生率分别是36.8%(21/57)和29.3%(12/41)。高眼压眼与无高眼压眼年龄(Z=-0.22)，性别(χ²=0.057)、手术眼别(χ²=0.612)，病程(Z=-0. 079)及手术时间(Z=-0.553)比较，差异均无统计学意义(P>0.05)。硅油眼和气体填充眼比较(χ²=1.04)、外伤眼和非外伤眼比较(χ²=0.044)，视网膜脱离眼和非视网膜脱离眼比较(χ²=2.282)，差异亦无统计学意义(P>0.05)。多次手术眼比首次手术眼高眼压发生率高(χ²=5.211)，联合手术较单纯玻璃体手术高(χ²=4.57)，无晶状体眼较有晶状体眼高(χ²=4.224)，差异有统计学意义(P<0.05)。

结论：23G免缝合微切口玻璃体切除术后高眼压主要发生在术后前3d。眼内手术史，联合手术，无晶状体眼是手术后高眼压的危险因素。

METHODS: Retrospective case series study. Totally 98 patients(98 eyes)who had undergone 23-gauge sutureless microincisional vitrectomy were enrolled. IOP was measured by non-contact tonometry. High IOP was defined as an IOP >25mmHg at any time within 7d after surgery. The influence of age, sex, side of operation, course of disease, primary disease pre-operation, reoperation, surgical options, type of tamponade, status of lens, surgical time on postoperative high IOP were analyzed.

RESULTS:High IOP was found in 33 eyes(33.7%)within 7d after surgery. High IOP was found in 8 eyes on postoperative 1d, the incidence was 24.2%(8/33), and 25 eyes was found on postoperative 3d, the incidence was 75.8%(25/33). The incidence of high IOP of male and female were 32.8%(20/61)and 35.1%(13/37)respectively. The incidence of high IOP of right and left eye were 36.8%(21/57)and 29.3%(12/41)respectively. There were no significant differences comparing age(Z=-0.22), sex(χ²=0.057), side of operation(χ²=0.612), course of disease(Z=-0.079)and surgical time(Z=-0.553)between patients with high IOP and those without it(P>0.05). Similarly, no statistical significance was found between eyes with gas tamponade and silicone oil tamponade(χ²=1.04), traumatic eyes and non traumatic eyes(χ²=0.044), and retinal detachment eyes and without retinal detachment eyes(χ²=2.282,P>0.05). The incidence of high IOP in eyes with several operations was higher than that in eyes with the first operation(χ²=5.211,P<0.05), in eyes with combined operations eyes was significantly higher than that in eyes with pure vitrectomy(χ²=4.57,P<0.05), and in eyes with aphakic eye was higher than that in eyes with phakic eyes(χ²=4.224,P<0.05).

CONCLUSION:High IOP occurs commonly in 3d after 23-gauge sutureless microincisional vitrectomy. The risk factors of high IOP are reoperation, combined operations and aphakic eye.