PAX6基因与视网膜疾病关系的研究进展

Research progress of the association between PAX6 gene and retinal diseases

摘要:

PAX6基因在胚胎发育过程中起重要作用，PAX6基因突变有可能导致先天性无虹膜、视网膜母细胞瘤、黄斑发育不良、Peters异常等眼病。本文主要就PAX6基因的基本背景知识以及PAX6与视网膜疾病的关系进行综述。

Abstract:

PAX6 gene plays an important role in embryological development, and the mutation of this gene may result incongenital aniridia, retinoblastoma, macula hypoplasia, Peters' anomaly and so on. A brief introduction of the background PAX6 gene, and the association between PAX6 and retinal diseases were summarized in this review.