深板层角膜移植术治疗病毒性角膜炎疗效观察

Clinical observation of deep lamellar keratoplasty for herpes simplex viral keratitis

摘要:

目的：探讨深板层角膜移植术治疗单疱病毒性角膜炎的临床疗效。

方法：对105例单疱病毒性角膜炎的患者行深板层角膜移植术。术后随访12～36mo，观察角膜移植片的透明度、视力及病毒性角膜炎复发情况。

结果：患者24例剥离角膜基质至接近后弹力层，81例中央区约6mm×6mm区域达到后弹力层。101例植床透明。术后视力均有不同程度的提高，最佳矫正视力>0.5者67例，0.3～0.5者35例，<0.3者3例。观察期内无病毒性角膜炎复发及排斥反应病例。

结论：深板层角膜移植术是治疗病毒性角膜炎的有效方法，对于视力较差发作频繁的病毒性角膜炎病例应早行手术治疗。

Abstract:

AIM: To investigate the clinical effects on the deep lamellar keratoplasty for herpes simplex keratitis.

METHODS: Deep lamellar keratoplasty was performed on 105 cases with herpes simplex viral keratitis. All of these patients were followed-up for 12-36mo, the corneal graft transparency, visual acuity and viral keratitis recurrence were observed.

RESULTS:Among 24 patients after stripping the corneal stroma which was close to the Descemet's membrane, Central area of 81 cases were about 6mm×6mm of to Descemet's membrane. One hundred and one cases of planting beds were transparent. Visual acuity were improved in varying degrees, best corrected visual acuity was greater than 0.5 in 67 cases, 0.3-0.5 in 35 cases, less than 0.3 in 3 cases. There was no recurrence of viral keratitis and rejection cases during the observation period.

CONCLUSION: Deep lamellar keratoplasty is an effective technique in the treatment of viral keratitis. It is therefore should be an early surgical treatment for frequent episodes of viral keratitis cases.