角膜穿孔临床研究分析
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Clinical research on corneal perforation
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    摘要:

    目的:研究角膜穿孔(corneal perforation,CP)患者的临床发病特点。

    方法:回顾性分析1995-07/2010-07福建医科大学附属第一医院住院确诊的CP患者72例72眼,分析其患者临床特点。

    结果:福建地区角膜溃疡穿孔发病率逐年上升,男女发病率比为 17:7 , 48岁为发病集中年龄,产业工人 23例(32%),23例有明确外伤史,菌属鉴定结果:前两位为:真菌感染和棘阿米巴原虫感染。 其中10例有糖皮质激素用药史。

    结论:外伤、真菌性、棘阿米巴角膜炎、蚕食性角膜炎等所致CP的原发病因多种多样,福建地区CP多发于中老年的男性,多数外伤为诱因,致病菌属以真菌感染为主。

    Abstract:

    AIM: To study the clinical characteristics of corneal perforation(CP).

    METHODS: A retrospective analysis in July 1995 to July 2010 the First Affiliated Hospital of Fujian Medical University diagnosed CP 72 patients(72 eyes), clinical characteristics of all the patients were analyzed.

    RESULTS: The incidence of corneal ulcer perforation rised year by year, the morbidity of male and female was 17:7, the onset age focused on 48 years old. Of 23 industrial workers(32%)with clear history of trauma, pathogeny identification results: top two: fungal infection and Acanthamoeba keratitis. A using history of glucocorticoid was found in 10 cases.

    CONCLUSION: There are plenty of primary causes of CP such as traumas, fungal infection, Acanthamoeba keratitis, eroded keratitis, etc. CP happens in middle-aged males in Fujian province, most traumas are the causes, the main pathogenic bacteria is fungal infection.

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董骋寰,薛龑,郑晓倩,等.角膜穿孔临床研究分析.国际眼科杂志, 2014,14(8):1502-1503.

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  • 收稿日期:2014-05-07
  • 最后修改日期:2014-07-10
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  • 在线发布日期: 2014-07-22
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