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[摘要]
目的:研究显微探针疏通技术在睑板腺功能障碍(meibomian gland dysfunction,MGD)治疗中的作用,以期为MGD的治疗提供快速有效、经济实用的治疗方法。
方法:选取直径为100μm的不锈钢丝作为材料,制作成总长度约3cm的探针,其中操作针头长约5mm,手柄长约2.5cm。选取睑板腺功能障碍性干眼症患者140例,分为两组并使其有可比性。观察组(n=70)利用显微探针对阻塞的睑板腺管进行疏通,配以药物、热敷、睑板腺按摩等治疗。对照组(n=70)给予常规给予药物、热敷、睑板按摩治疗。对两组患者治疗后1d; 1,2wk; 1,2,3mo的BUT、有效率及治愈率进行比较。
结果:观察组与对照组经过治疗后BUT均明显延长,且观察组改善更为明显; 治疗后1d; 1,2wk; 1,2,3mo观察组治愈率、有效率均明显高于对照组。
结论:利用显微探针对睑板腺管进行疏通,能为MGD的治疗提供快速有效、经济实用的治疗方法,可以在临床中进行推广。
[Key word]
[Abstract]
AIM: To evaluate the function of the microprobe dredging technology in the treatment of meibomian gland dysfunction(MGD)and to provide fast, efficient, economical and practical method of treatment for meibomian gland dysfunction(MGD).
METHODS:The 100μm diameter stainless steel wire was made as the microprobe with the total length of 3cm, which the needle was about 5mm and hand shank was about 2.5cm. Selected 140 cases with dry eyes of meibomian gland dysfunction(MGD), patients were divided into two groups and made them have comparability. Observation group(n=70)used microprobe to dredge meibomian gland pipe accompanied with drugs, hot compress and meibomian gland massage treatment. The control group(n=70)was given conventional drugs, hot compress and meibomian massage treatment. To compare the tear break-up time(BUT), efficient rate and the cure rate of the two groups after treatment of 1d, 1wk, 2wk, 1 mo, 2mo and 3mo.
RESULTS: BUT were significantly prolonged in observation group and control group after treatment, and the observation group improved more obviously; the efficient rate and cure rate of the observation group were significantly higher than that of the control group after 1d, 1wk, 2wk, 1mo, 2mo and 3mo treatment.
CONCLUSION:Using microprobe to unclog the meibomian gland tube can provide the fast and efficient, economical and practical treatment for meibomian gland dysfunction(MGD), which can be promoted in the clinical practice.
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