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[摘要]
谱域光学相干断层扫描技术(spectral-domain optical coherence tomography,SD-OCT)的革新可以协助我们更好地观察新生血管性老年性黄斑变性(neovascular age-related macular degeneration,NVAMD)的病程进展,并且监测其治疗效果。抗血管内皮生长因子(anti-vascular endothelial growth factor,抗VEGF)药物治疗这种新型方法,已被证实可以有效治疗NVAMD,然而治疗后的长期随访和再治疗成为维持现有视力的关键问题。在抗VEGF治疗过程中, SD-OCT成像有助于早期识别脉络膜新生血管的复发。本文将进一步阐述在NVAMD患者接受玻璃体腔注射抗VEGF治疗后,SD-OCT在随访中的作用。
[Key word]
[Abstract]
Advances in spectral-domain optical coherence tomography(SD-OCT)technology provide improved monitoring of progression and assistance in quantifying response to treatment modalities in neovascular age-related macular degeneration(NVAMD). There is little doubt that anti-vascular endothelial growth factor(anti-VEGF)drug therapy is becoming a new approach to the management of NVAMD, while long-term follow-up and necessary retreatments are the key issues to remain obtained visual acuity.SD-OCT imaging helps to identify early recurrence of choroidal neovascularization during treatment with anti-VEGF. This review discusses the present applications of the commercially available SD-OCT systems in the follow-up of after the injection of intravitreal anti-VEGF in NVAMD.
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