目的：比较盐酸环喷托酯滴眼液和阿托品眼用凝胶在12岁以下远视儿童散瞳检影验光结果，以评估盐酸环喷托酯滴眼液在远视验光中的临床使用价值。

方法：年龄2～12岁的远视儿童51例102眼，先用10g/L盐酸环喷托酯滴眼液连续点眼5次后验光，间隔1d后，再用10g/L硫酸阿托品眼用凝胶连续点眼3d后进行散瞳检影验光。分析比较两种睫状肌麻痹剂在不同屈光组的验光结果及全身不良反应。

结果：轻度远视31眼两种验光结果无统计学差异(P>0.05)，中度远视组39眼两种验光结果无统计学差异(P>0.05)，高度远视组32眼两种验光结果无统计学差异(P>0.05)。10g/L盐酸环喷托酯滴眼液的全身不良反应发生率为2%，10g/L阿托品眼用凝胶全身不良反应发生率为8%。

结论：盐酸环喷托酯滴眼液是一种起效快、作用强、持续时间短的安全有效的新型睫状肌麻痹剂，临床上可广泛应用。

AIM: To compare the cyclopentolate hydrochloride eye drops and atropine ophthalmic gel in 12 years old of the following children with hyperopia mydriatic optometry results, in order to assess cyclopentolate hydrochloride drops of clinical value to use eye drops in hyperopia refraction.

METHODS: Fifty-one cases(102 eyes), aged 2-12 years old children with hyperopia, first with 10g/L cyclopentolate hydrochloride eye drops 5 times continuously after optometry, interval of 1d, with 10g/L atropine sulfate eye 3d mydriatic optometry gel for eyes. Analysis and comparison of two kinds of cycloplegic refraction in different groups of optometry results and systemic adverse reactions.

RESULTS: Thirty-one eyes with gentle hyperopia refraction results were no statistical difference(P>0.05), 39 eyes with moderate hyperopia refraction results were no statistical difference(P>0.05), 32 eyes with high myopia refraction results were no statistical difference(P>0.05). Systemic adverse reactions of the 10g/L cyclopentolate hydrochloride eye drops were 2%, 10g/L atropine eye gel systemic adverse reaction rate was 8%.

CONCLUSION:Cyclopentolate hydrochloride eye drops is a new cycloplegic with fast onset, strong action, short duration, safe and effective, which can be wildly used clinically.

重庆市科学技术委员会重点攻关项目(No.2010GGB012)