方法：对186例372眼近视患者施行LASEK手术，随机分为观察组和对照组，激光切削后分别配戴-1.0D基弧为8.7，8.5mm的软性角膜接触镜。术后1，3，5d比较两组术后角膜刺激症状，术后5d比较角膜上皮愈合时间、裸眼视力，术后1mo比较两组裸眼视力，术后3mo比较角膜上皮下雾状混浊(haze)程度。

结果：术后1，3，5d观察组角膜刺激症状明显好于对照组，差异有统计学意义(P<0.05)。术后5d角膜上皮愈合时间、裸眼视力观察组明显好于对照组，差异有统计学意义(P<0.05)。术后1mo两组裸眼视力无明显差别，差异无统计学意义(P>0.05)。术后3mo两组haze比较差异无统计学意义(P>0.05)。

结论：LASEK术后应适当增加需配戴的软性角膜接触镜的基弧，可以减轻角膜刺激症状，促进角膜上皮愈合和视力恢复。

METHEDS: Totally 186 cases(372 eyes)with myopia underwent LASEK surgery were divided into the observation group and the control group randomly, respectively wearing soft corneal lens -1.0D with 8.7mm and 8.5mm base curve. The comparison and observation were conducted in terms of corneal irritation at postoperative 1, 3 and 5d, the time of healing the epithelium and visual recovery in these two groups at 5d, the uncorrected visual acuity refraction at 1mo, and the degree of haze at 3mo.

RESULTS: Corneal irritation in the observation group was much better than that in the control group at postoperative 1, 3 and 5d, there was significant difference(P<0.05). There was significant difference in the healing of epithelium and uncorrected visual acuity at postoperative 5d, the difference was significant(P<0.05). There was no significant difference of the uncorrected visual acuity at postoperative 1mo(P>0.05), and there was no significant difference of haze at postoperative 3mo between two groups(P>0.05).

CONCLUSION: Wearing bigger base curve soft corneal contact lens is a safe and efficient method for LASEK than smaller with the advantages of having mild irritating symptom, a shorter time of healing the epithelium and the visual acuity.