Choroid neovascularization(CNV)is more common in age-related macular degeneration, pathological myopia macular degeneration and central exudative chorioretinopathy and so on, and it is the leading cause of vision loss and even lost. In the treatment, laser photocoagulation, transpupillary thermotherapy(TTT)and photodynamic therapy(PDT)have been widely carried out in our country; And resistance to new blood vessels formation and pathological process of inflammatory reaction of drugs used in clinic were also significantly increased. In recent years, the new methods such as gene therapy, targeted treatment of CNV also get achievements, now we summarize the research status at home and abroad about the treatment of CNV.