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[摘要]
目的:观察法舒地尔治疗非动脉炎性缺血性视神经病变的临床效果。
方法:自2012-03/2013-06收治的缺血性视神经病变患者70例随机分为观察组(法舒地尔治疗组)和对照组(常规治疗组)各35例,治疗周期均为4wk,观察比较两组的最佳矫正视力和视野。
结果:观察组最佳矫正视力总有效率为86%; 对照组总有效率为57%,两组比较差异显著,具有统计学意义(P<0.05)。观察组视野好转率为83%,对照组视野好转率为57%,两组比较差异显著,具有统计学意义(P<0.05)。
结论:法舒地尔治疗非动脉炎性缺血性视神经病变效果优于传统药物。
[Key word]
[Abstract]
AIM:To evaluate the clinical effects of fasudil therapy on nonarteritic anterior ischemic optic neuropathy(NAION).
METHODS:Seventy eyes of 70 patients with NAION in our hospital were collected and randomly divided into treatment group(35 patients)which was intravenously injected fasudil, and control group(35 patients)which was intravenously injected composite salvia miltiorrhiza injection. At the 4wk of follow-up, the best corrected visual acuity(BCVA)and visual field were observed and compared.
RESULTS: The total effective rate of BCVA in treatment group was 86%, in control group was 57%. The difference in two groups had statistical significance(P<0.05). The improvement rate of visual field in treatment group was 83% and in control group was 57%. The difference in two groups had statistical significance(P<0.05)
CONCLUSION:The clinical effects of fasudil on NAION are better than conventional medication.
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