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[摘要]
目的:研究黏弹物质小管切开术和超声黏弹物质小管切开术治疗眼压失控的成功率及并发症。在Nd: YAG前房角穿刺后,检测并发症及结果。
方法:评估1a内进行黏弹物质小管切开术和超声黏弹物质小管切开术时收集预期的数据。除此之外,Nd:YAG激光房角穿孔术(LGP)应用于术后任何时期的眼压失控。
结果:符合纳入条件并能获得随访数据者100眼。76%(76眼)完全成功(未经青光眼治疗眼内压≤18mmHg),88%(88眼)合格成功(眼内压≤18mmHg,伴或者不伴永久性青光眼的治疗)。63%(63眼)在未用药的情况下眼内压下降了30%,67%(67眼)伴或者不伴有永久性青光眼的治疗。Kaplan-Meier生存分析建议超声黏弹物质小管切开术在未用药的情况下把眼压降到18mmHg,时序检验P=0.005。16眼在不同的时间点需要术后激光房角穿孔,大多数在术后6mo发作。平均眼内压术后减少24.8%(P=0.0002)。激光房角穿孔术后第12mo未经治疗的眼内压小于18mmHg的达到94%(15眼)。所有患者在激光房角穿孔术后至少3mo眼内压保持下降趋势,后期将继续进行随访。
结论:我们的数据显示黏弹物质小管切开术和超声黏弹物质小管切开术在这随访1a内能成功控制眼内压。Nd: YAG激光房角穿孔术在降低和保持眼内压方面也很有成效。几乎没有并发症。
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[Abstract]
AIM: To evaluate the outcomes, success rate and complications encountered following viscocanalostomy and phacoviscocanalostomy. And to quantify our need, complications and results following Nd:YAG goniopuncture.
METHODS: Data was collected prospectively on eyes undergoing viscocanalostomy or phacoviscocanalostomy and evaluation was carried out at 1 year. In addition Nd:YAG laser goniopuncture(LGP)was performed at any stage for uncontrolled post-operative IOP.
RESULTS: Post-operative data was available for 100 eyes. Eyes achieving complete success(defined as IOP≤18mmHg without any glaucoma medication)was 76%(n=76), and those with a qualified success(defined as a total of eyes with an IOP≤18mmHg without or with 1 permanent glaucoma medications)was 88%(n=88). Sixty-three percent(n=63)of eyes achieved a 30% reduction in IOP without a need for medication and 67%(n=67)in total without or with 1 permanent glaucoma medication. The Kaplan-Meier survival analysis suggests phacoviscocanalostomy is superior at lowering the IOP to less than 18mmHg without medication, log rank test P=0.005. Sixteen eyes required post operative LGP at various time points, a majority(40%)of episodes were around 6 months post surgery. There was a 24.8% post LGP reduction in mean IOP(P=0.0002). For LGP at 12 months an IOP less than 18mmHg without glaucoma treatment was achieved in 94%(n=15)following LGP. All patients maintained a drop in IOP at least 3 months following LGP, longer follow up data was to follow.
CONCLUSION: Our data show viscocanalostomy and phacoviscocanalostomy are highly successful at 1 year. Nd:YAG laser goniopuncture was also efficacious at lowering and maintaining the IOP. Complications were scarce.
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