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[摘要]
目的: OCT观察累及黄斑视网膜脱离行巩膜外加压术后5a黄斑情况。分析脱离时间及术后5a黄斑OCT及视功能的相关性。
方法:回顾性分析47例47眼,累及黄斑视网膜脱离行巩膜外加压术后5a OCT, 视功能及脱离时间,并行统计学分析。
结果:视网膜脱离时间<7d的黄斑厚度(226SymbolqB@88μm)较脱离时间>7d黄斑厚度(209SymbolqB@76μm)厚, 但无统计学意义。而术后复位的黄斑厚度和视力呈正相关(Pearson correlation test, R=1,P=0.01)。脱离时间<7d组视力(0.53)明显好于脱离时间>7d组视力(0.25),明显统计学差异(t-test, P=0.008)。5例(10%)患者发现黄斑区结构异常,包括4例IS/OS层断裂,同时伴有外界膜的断裂(8.5%),且术后5a平均视力(0.15)低于两组的平均视力。
结论:脱离时间的长短严重影响视功能的恢复、术后黄斑的厚度及黄斑结构的改变。累计黄斑视网膜脱离手术尽可能在脱离时间<7d内完成。对于视力恢复较差者,建议行OCT检查。
[Key word]
[Abstract]
AIM: To observe the macula structure of the macula-off rhegmatogenous retinal detachment(RRD)with optical coherence tomography(OCT)5 years after successful scleral buckling(SB)surgery and to analyze the correlation between the duration of macular detachment(DMD)and postoperative visual acuity with OCT image.
METHODS: Forty-seven eyes of 47 patients with macula-off RRD were retrospectively studied and follow-up was carried out for a period of 5 years. The correlation among the postoperative best-corrected visual acuity(VA), the DMD and the microstructural findings with OCT at the fovea were evaluated.
RESULTS: The sub-acute RRD(DMD<7d)shows a greater foveal thickness(226SymbolqB@88μm)than the prolonged one(DMD>7 days)(209SymbolqB@76μm)with no statistical difference(P=0.791). Meanwhile, the sub-acute RRD had better mean final VA 0.53, compared with the prolonged one of 0.25, with significant difference(Student's t-test, P=0.008). Among 47 eyes, foveal anatomic abnormalities were detected in 5 eyes(10%); disruption of the junction between the photoreceptor inner and outer segments(IS/OS)in 4 eyes, and with a disrupted external limiting membrane(ELM)also(8.5%); and the mean VA of these 5 patients was 0.15 lower after 5 years.
CONCLUSION: Sub-acute macula-off RRD has a better impact on the final visual recovery than the prolonged one. Furthermore, the retinal thickness in the fovea was positively correlated to the postoperative VA. The disrupted inner segment/outer segment(IS/OS)junction could be restored in the patients without disrupted ELM signals at the initial examination. The duration of macula-off RRD within 7d had fewer disrupted inner segment/outer segment(IS/OS)junction with disrupted ELM signals than those for more than 7d. It is recommended to perform OCT in cases where VA was not improved as expected.
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