目的：比较白内障术前应用不同浓度聚维酮碘溶液结膜囊冲洗，术后眼内炎和不良反应发生率，以评价50g/L浓度聚维酮碘溶液预防白内障术后眼内炎的有效性、安全性。

方法：将500例白内障手术治疗患者分为50g/L聚维酮碘组和25g/L聚维酮碘组，术中、术后观察眼部体征并询问患者主观不适。

结果：50g/L聚维酮碘组眼部刺激症状较25g/L聚维酮碘组明显，但角膜上皮脱失情况和眼内炎的发生两组无区别。

结论：术前结膜囊内使用50g/L聚维酮碘溶液是一种有效、安全的预防白内障术后眼内炎的措施。

AIM: To evaluate the efficiency and safety of 50g/L povidone-iodine solution in preventing postoperative endophthalmitis through comparing the incidence of postoperative endophthalmitis and adverse reactions after conjunctival sac washing with povidone-iodine of different concentrations.

METHODS: Totally 500 cataract patients were divided into 50g/L povidone-iodine group and 25g/L povidone-iodine group. All the operated eyes were observed during and after surgery.The patients' subjective discomfort was inquired and their signs of eyes were recorded.

RESULTS: The eye irritation of 50g/L povidone-iodine group was more significant than 25g/L povidone-iodine group. No significant difference in the corneal epithelial loss and endophthalmitis was observed between two groups.

CONCLUSION:Conjunctival sac washing with 50g/L povidone-iodine is an effective and safe measure to prevent endophthalmitis after cataract surgery.