方法：复发性角膜上皮糜烂的门诊患者22例23眼，最初均采用保守药物治疗无效或反复后，采用角膜浅基质针刺联合配戴绷带式隐形眼镜治疗。治疗前所有患者均表现晨起或晚间异物感、流泪、眼睑痉挛、畏光，部分伴有轻度视力下降。表面麻醉后，在裂隙灯下，用4号半针头制成截囊针形状，尖端长0.3mm，垂直穿过疏松的上皮和前弹力层行角膜浅基质多点针刺，术毕配戴月抛式绷带式隐形眼镜。在治疗后3d； 1，2，4，8，12wk共6个时间点观察患者异物感、视力、畏光、上皮愈合情况及基质瘢痕情况。平均随访3mo。

结果：患者22例23眼中，22眼症状完全消失，一次治愈19眼，成功率83%。

结论：针对常规药物治疗方法无效的复发性角膜上皮糜烂患者，角膜浅基质针刺联合绷带式隐形眼镜配戴是一种有效、便捷、可重复执行、经济的治疗方法，迅速改善患者眼部不适症状，具有临床实用价值。

METHODS: ASP was used as a treatment for 23 eyes of 22 outpatients with recurrent epithelial defects. At the mean time, they wore bandage contact lens and used eyedrops. All patients report foreign-body sensation, blepharospasm, tearing and photophobia in the morning or evening, some with visual impairment. ASP was performed on every patient with a self-made 41/2 needle under surface anesthesia. The patients worn contact lens after the surgery. We observed symptoms of foreign-body sensation, photophobia, vision,epithelial and stromal scar healing at 3d; 1,2,4,8,12wk. The average follow-up period was 3 months, range 4wk-10mo.

RESULTS: Twenty-two eyes became completely asymptomatic and 19 eyes(83%)were once cured.

CONCLUSION:ASP with bandage contact lens turns out to be an effective, convenient, economical and repeatable therapeutic option for patients with recurrent epithelial defects, which can control the severe foreign-body sensation quickly.