[关键词]
[摘要]
目的:探讨丝裂霉素C(MMC)在慢性闭角型青光眼患者行青光眼白内障联合手术中的价值,为青光眼合并白内障的临床治疗提供参考。
方法:将40例慢性闭角型青光眼合并白内障患者随机分为观察组(使用MMC组)和对照组(未使用MMC组),均行晶状体超声乳化联合小梁切除术治疗,比较治疗效果。
结果:观察组治疗后患者远视力(矫正)、周围前房深度、眼压及降眼压药物使用数量与种类均优于对照组,且与对照组比较,均P<0.05,具有统计学差异。观察组功能性滤过泡的比例与对照组比较,两组差异无统计学意义(P>0.05)。两组治疗主要并发症为术后浅前房,其中,观察组1例(5%),对照组2例(10%),两组比较差异无统计学意义(P>0.05)。
结论:MMC能改善慢性闭角型青光眼患者行青光眼白内障联合手术后的眼压、视力,建议推广使用。
[Key word]
[Abstract]
AIM: To investigate the value of mitomycin C(MMC)in chronic angle-closure glaucoma patients with glaucoma and cataract, and to provide reference for the clinical treatment.
METHODS: Forty patients with chronic angle-closure glaucoma and cataract patients were randomly divided into the observation group(MMC group)and the control group(NonMMC group). Phacoemulsification and trabeculectomy was used for the treatment. The treatment effects were compared.
RESULTS: After treatment, the distance vision(corrected), peripheral anterior chamber depth, intraocular pressure and the number and types of the IOP drug of observation group were all better than those of the control group(all P<0.05). There was no statistically significant difference of the proportion of functional blebs of the two groups(P>0.05). The main complications after the treatment was shallow anterior chamber, in which the observation group was 1 case(5%)and the control group were 2 cases(10%)(P>0.05).
CONCLUSION:MMC in chronic angle-closure glaucoma patients with glaucoma and cataract could improve the intraocular pressure, visual acuity and should be recommended for clinical treatment.
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