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[摘要]
目的:探讨预防性玻璃体切割手术对急性视网膜坏死综合征的治疗效果。
方法:患者26例33眼分为两组,常规治疗组20眼接受常规治疗,包括抗病毒治疗、视网膜脱离发生后给予玻璃体切割手术治疗; 及时玻璃体切割手术组13眼给予抗病毒治疗及预防性玻璃体切割手术治疗。术后患者随访6~48mo。
结果:在常规治疗组,发生视网膜脱离11眼(55%),眼球萎缩4眼(20%),视力提高者3眼(15%),预防性玻璃体切割手术治疗组,发生视网膜脱离1眼(8%),视力提高者5眼(38%)。预防性玻璃体切割手术组视网膜脱离发生率较常规治疗组低(P<0.05)。
结论:预防性玻璃体切割手术可以有效地降低视网膜脱离的发生率,改善急性视网膜坏死综合征的预后。
[Key word]
[Abstract]
AIM: To evaluate the efficacy of prophylactic vitrectomy for acute retinal necrosis syndrome(ARNS).
METHODS: Twenty-six patients(33 eyes)were retrospectively included in this study. The eyes were divided into 2 groups by treatment, including routine treatment, which consisted of antiviral medication and vitrectomy after retinal detachment(RD)(n=20), and prophylactic vitrectomy, which consisted of antiviral medication and vitrectomy for the prevention of RD performed during the active inflammatory phase(n=13). The follow-up period ranged from 6 to 48 months.
RESULTS: In the routine treatment group, retinal detachment occurred in 11 eyes(55%), 4 eyes(20%)developed ocular atrophy, 3 eyes(15%)achieved increased visual acuity. In the prophylactic vitrectomy group, RD occurred in 1 eyes(8%), 5 eyes(38%)achieved increased visual acuity. There was lower incident of retinal detachment in the prophylactic vitrectomy group than that in the routine treatment group(P<0.05).
CONCLUSION: Prophylactic vitrectomy can prevent RD and improve the prognosis of ARNS.
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