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[摘要]
目的:了解不同程度远视屈光不正性弱视儿童的图形视觉诱发电位(Pattern visual evoked potential, P-VEP)特征。
方法:2011-05/2012-08在我院就诊的远视屈光不正性弱视儿童,按不同最佳矫正视力(best corrected vision acuity, BCVA)分为3组,P-VEP检查分析比较不同组间及与正常儿童的P100波峰潜时和振幅的变化。
结果:正常组P100波峰潜时101.43±6.82ms,P100波振幅为11.27±5.38μV。在不同程度弱视组间P100波峰较正常组潜时延迟,分别为视力高于0.5组110.54±8.47ms,视力0.3~0.5组118.76 ±6.21ms,视力低于0.3组124.54±7.36ms,且各组间差异有统计学意义(P<0.05)。P100波振幅均较正常下降,分别为轻度组 9.94±5.28μV,中度组8.57±7.21μV,重度组7.49±5.07μV,各组间比较差异有统计学意义(P<0.05)。
结论:远视屈光不正弱视儿童的图形视觉诱发电位弱视眼的P100波峰潜时延迟、P100波振幅下降。且P100波峰潜时延迟、P100波振幅下降与弱视程度相关。
[Key word]
[Abstract]
AIM: To observe pattern visual evoked potential(P-VEP)of varying degrees hyperopic refractive amblyopic children.
METHODS: We did P-VEP examination for the hyperopic refractive children from May 2011 to August 2012. We divided these children into three groups according to different best corrected vision(BCV): better than 0.5 amblyopic group, 0.3-0.5 amblyopic group and lower than 0.3 amblyopic group. Their P100 latency and amplitude were measured and compared with normal children group.
RESULTS: The healthy eye's P100 latency was 101.43±6.82ms, P100 amplitude was 11.27±5.38μV. P100 latency delay and P100 amplitude decline in amblyopic group. Better than 0.5 amblyopic group, 110.54±8.47ms, 9.94±5.28μV; 0.3-0.5 amblyopic group 118.76±6.21ms, 8.57±7.21μV; and lower than 0.3 amblyopic group 124.54±7.36ms, 7.49±5.07μV. P100 latency and amplitude have significant different between groups(P<0.05).
CONCLUSION: P100 latency delay and P100 amplitude decline in hyperopic refractive amblyopia and the changes are associated with degree of amblyopia.
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