散血明目片联合复方樟柳碱治疗眼缺血综合症

Effects of sanxuemingmu capsule combined with compound anisoine in ocular ischemic diseases

摘要:

目的：研究散血明目片联合复方樟柳碱对眼缺血综合症的治疗效果。

方法：采用随机病例对照的方式，根据入组患者既往是否使用活血祛瘀药物治疗情况分层，再分组，并予以相应治疗干预3周期后，通过视力、视野、眼部彩超等改善情况观察药物的临床疗效及不良反应的发生率。

结果：各实验组在综合疗效、视力、平均视敏度下降、FFA动、静脉充盈时间、CDI各项指标比较，均有所改善，心血管不良反应发生率低，有显著统计学差异。

结论：散血明目片联合复方樟柳碱对眼缺血综合症均有良好的临床疗效，并能减少心血管不良反应的发生率，且联合用药的疗效对既往未接受相关药物的患者更为确切。

Abstract:

AIM: To evaluate the effects of sanxuemingmu capsule combined with compound anisoine in the ocular ischemic disease.

METHODS: We divided our patient into two groups according to their blood-activating and stasis-dissolving drug using history at first, then divided them into observation/positive/negative control subgroups according to random case-control method. The clinical key data and advert effects after 3 cycles of treatment were obtained by visual acuity/visual field and color Doppler.

RESULTS: The index of general effects/visual acuity/the general visual acuity loss/the artery/vein perfusion time of fundus fluorescein angiography(FFA)and color Doppler index(CDI)together with the advert effects rate of cardiovascular system of the observation groups were significantly better than those of the contrast groups.

CONCLUSION: The combination of sanxuemingmu capsule with anisoine is effective in the ocular ischemic diseases and can lessen the cardiovascular advert effect rate of ocular ischemic diseases suffer while this administration method is more benefit in cases without blood-activating and stasis-dissolving drug using history than cases with drug using cases.